Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes

H. A. Mohamed, M. Khuphe, S. J. Boardman, Samantha Shepherd, Roger Phillips, P.D. Harvey, Charlotte E. Willans

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Amphiphilic block copolymers have been developed for the encapsulation of organometallic drugs. Silver-N-heterocyclic carbene complexes have shown significant promise as anticancer and antibacterial compounds, and have been studied as the payload in these carriers. Simple modification of the N-heterocyclic carbene ligand structure enables solubility properties and interaction with the polymer to be tuned.
Original languageEnglish
Pages (from-to)10474-10477
Number of pages4
JournalRSC Advances
Volume8
Issue number19
Early online date15 Mar 2018
DOIs
Publication statusPublished - 2018

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Organometallics
Encapsulation
Silver
Block copolymers
Polymers
Solubility
Ligands
Pharmaceutical Preparations
carbene

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Mohamed, H. A., Khuphe, M., Boardman, S. J., Shepherd, S., Phillips, R., Harvey, P. D., & Willans, C. E. (2018). Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes. RSC Advances, 8(19), 10474-10477. https://doi.org/10.1039/C8RA00450A
Mohamed, H. A. ; Khuphe, M. ; Boardman, S. J. ; Shepherd, Samantha ; Phillips, Roger ; Harvey, P.D. ; Willans, Charlotte E. / Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes. In: RSC Advances. 2018 ; Vol. 8, No. 19. pp. 10474-10477.
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Mohamed, HA, Khuphe, M, Boardman, SJ, Shepherd, S, Phillips, R, Harvey, PD & Willans, CE 2018, 'Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes', RSC Advances, vol. 8, no. 19, pp. 10474-10477. https://doi.org/10.1039/C8RA00450A

Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes. / Mohamed, H. A.; Khuphe, M.; Boardman, S. J.; Shepherd, Samantha; Phillips, Roger; Harvey, P.D.; Willans, Charlotte E.

In: RSC Advances, Vol. 8, No. 19, 2018, p. 10474-10477.

Research output: Contribution to journalArticle

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