Potential Synthetic Biolubricant as an Alternative to Bovine Serum

Susan Scholes, Coral Colledge, Andrew Naylor, Mohammed Mahdi, Alan Smith, Thomas Joyce

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

It is crucial that orthopaedic implant materials are tested in conditions that replicate the natural body’s environment as closely as possible. Bovine serum is currently recommended for use by the International Organisation for Standardisation (ISO) for the wear testing of these implant materials, however, the rheological properties of bovine serum do not match fully those of the body’s natural lubricant, synovial fluid. This study looks at a potential alternative to bovine serum for the testing of orthopaedic implant materials; 0.5% gellan gum fluid gel. Wear tests using multidirectional motion were conducted on ultra-high molecular weight polyethylene (UHMWPE) pins rubbing against stainless steel plates. Roughness measurements were performed during testing along with particle analysis of the testing lubricant. At two million cycles (equivalent to 121.3 km of sliding), the mean wear factor for the four UHMWPE pins was 0.25 (standard deviation (SD) 0.03) 10-6 mm3/Nm and there was no evidence of any transfer film on the plate surfaces. The wear factor produced by 0.5% gellan gum fluid gel was lower than that measured in previous studies using bovine serum as the lubricant but greater than the wear factor shown in published work using a similar alternative lubricant (sodium alginate mixed with gellan gum). Work on the development of a suitable alternative lubricant to bovine serum will continue.
LanguageEnglish
Article number38
Number of pages14
JournalLubricants
Volume4
Issue number4
DOIs
Publication statusPublished - 18 Nov 2016

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Lubricants
Wear of materials
Ultrahigh molecular weight polyethylenes
Orthopedics
Testing
Fluids
Gels
Roughness measurement
Sodium alginate
Standardization
Stainless steel

Cite this

Scholes, S., Colledge, C., Naylor, A., Mahdi, M., Smith, A., & Joyce, T. (2016). Potential Synthetic Biolubricant as an Alternative to Bovine Serum. Lubricants, 4(4), [38]. https://doi.org/10.3390/lubricants4040038
Scholes, Susan ; Colledge, Coral ; Naylor, Andrew ; Mahdi, Mohammed ; Smith, Alan ; Joyce, Thomas. / Potential Synthetic Biolubricant as an Alternative to Bovine Serum. In: Lubricants. 2016 ; Vol. 4, No. 4.
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Scholes, S, Colledge, C, Naylor, A, Mahdi, M, Smith, A & Joyce, T 2016, 'Potential Synthetic Biolubricant as an Alternative to Bovine Serum', Lubricants, vol. 4, no. 4, 38. https://doi.org/10.3390/lubricants4040038

Potential Synthetic Biolubricant as an Alternative to Bovine Serum. / Scholes, Susan; Colledge, Coral; Naylor, Andrew; Mahdi, Mohammed; Smith, Alan; Joyce, Thomas.

In: Lubricants, Vol. 4, No. 4, 38, 18.11.2016.

Research output: Contribution to journalArticle

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T1 - Potential Synthetic Biolubricant as an Alternative to Bovine Serum

AU - Scholes, Susan

AU - Colledge, Coral

AU - Naylor, Andrew

AU - Mahdi, Mohammed

AU - Smith, Alan

AU - Joyce, Thomas

PY - 2016/11/18

Y1 - 2016/11/18

N2 - It is crucial that orthopaedic implant materials are tested in conditions that replicate the natural body’s environment as closely as possible. Bovine serum is currently recommended for use by the International Organisation for Standardisation (ISO) for the wear testing of these implant materials, however, the rheological properties of bovine serum do not match fully those of the body’s natural lubricant, synovial fluid. This study looks at a potential alternative to bovine serum for the testing of orthopaedic implant materials; 0.5% gellan gum fluid gel. Wear tests using multidirectional motion were conducted on ultra-high molecular weight polyethylene (UHMWPE) pins rubbing against stainless steel plates. Roughness measurements were performed during testing along with particle analysis of the testing lubricant. At two million cycles (equivalent to 121.3 km of sliding), the mean wear factor for the four UHMWPE pins was 0.25 (standard deviation (SD) 0.03) 10-6 mm3/Nm and there was no evidence of any transfer film on the plate surfaces. The wear factor produced by 0.5% gellan gum fluid gel was lower than that measured in previous studies using bovine serum as the lubricant but greater than the wear factor shown in published work using a similar alternative lubricant (sodium alginate mixed with gellan gum). Work on the development of a suitable alternative lubricant to bovine serum will continue.

AB - It is crucial that orthopaedic implant materials are tested in conditions that replicate the natural body’s environment as closely as possible. Bovine serum is currently recommended for use by the International Organisation for Standardisation (ISO) for the wear testing of these implant materials, however, the rheological properties of bovine serum do not match fully those of the body’s natural lubricant, synovial fluid. This study looks at a potential alternative to bovine serum for the testing of orthopaedic implant materials; 0.5% gellan gum fluid gel. Wear tests using multidirectional motion were conducted on ultra-high molecular weight polyethylene (UHMWPE) pins rubbing against stainless steel plates. Roughness measurements were performed during testing along with particle analysis of the testing lubricant. At two million cycles (equivalent to 121.3 km of sliding), the mean wear factor for the four UHMWPE pins was 0.25 (standard deviation (SD) 0.03) 10-6 mm3/Nm and there was no evidence of any transfer film on the plate surfaces. The wear factor produced by 0.5% gellan gum fluid gel was lower than that measured in previous studies using bovine serum as the lubricant but greater than the wear factor shown in published work using a similar alternative lubricant (sodium alginate mixed with gellan gum). Work on the development of a suitable alternative lubricant to bovine serum will continue.

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KW - orthopedic

KW - pin-on-plate

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KW - ultra-high molecular weight polyethylene

KW - wear testing

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DO - 10.3390/lubricants4040038

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