Powder Compaction: Compression Properties of Cellulose Ethers

Research output: Contribution to journalReview article

Abstract

ffective development of matrix tablets requires a comprehensive understanding of different raw material attributes and their impact on process parameters. Cellulose ethers (CE) are the most commonly used pharmaceutical excipients in the fabrication of hydrophilic matrices. The innate good compression and binding properties of CE enable matrices to be prepared using economical direct compression (DC) techniques. However, DC is sensitive to raw material attributes, thus, impacting the compaction process. This article critically reviews prior knowledge on the mechanism of powder compaction and the compression properties of cellulose ethers, giving timely insight into new developments in this field.
Original languageEnglish
Pages (from-to)19-29
JournalBritish Journal of Pharmacy
Volume1
Issue number1
DOIs
Publication statusPublished - 14 Nov 2016

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