Probing the impact of porosity on swelling kinetics of hydrophilic matrices

Muhammad Asim; Muhammad Usman  Ghori; Barbara Conway

doi:10.5920/bjpharm.2017.16

Probing the impact of porosity on swelling kinetics of hydrophilic matrices

Muhammad Asim, Muhammad Usman Ghori, Barbara Conway

Research output: Contribution to journal › Conference article › peer-review

Abstract

The aim of the present investigation was to understand the swelling behaviour of HPMC and PEO-based matrices and to evaluate the impact of porosity on the swelling kinetics. It was noticed that the HPMC has higher swelling rates but both undergo diffusion oriented swelling mechanism. It could also the concluded that the porosity has a marked influence in the development of gel layer on the surface of these matrices.

Original language	English
Pages (from-to)	S11-S13
Number of pages	3
Journal	British Journal of Pharmacy
Volume	2
Issue number	2
DOIs	https://doi.org/10.5920/bjpharm.2017.16
Publication status	Published - 4 Dec 2017
Event	8th Academy of Pharmaceutical Science International PharmSci Conference: Pharmaceutical Science Without Borders - University of Hertfordshire, Hatfield, United Kingdom Duration: 5 Sep 2017 → 7 Sep 2017 Conference number: 8 https://www.apsgb.co.uk/blog/Default.asp?D_A=20161101 (Link to Conference Information)

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10.5920/bjpharm.2017.16Licence: CC BY

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title = "Probing the impact of porosity on swelling kinetics of hydrophilic matrices",

abstract = "The aim of the present investigation was to understand the swelling behaviour of HPMC and PEO-based matrices and to evaluate the impact of porosity on the swelling kinetics. It was noticed that the HPMC has higher swelling rates but both undergo diffusion oriented swelling mechanism. It could also the concluded that the porosity has a marked influence in the development of gel layer on the surface of these matrices.",

keywords = "matrix tablet, porosity, swelling, compaction",

author = "Muhammad Asim and Ghori, {Muhammad Usman} and Barbara Conway",

year = "2017",

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language = "English",

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note = "8th Academy of Pharmaceutical Science International PharmSci Conference : Pharmaceutical Science Without Borders, APS ; Conference date: 05-09-2017 Through 07-09-2017",

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AU - Asim, Muhammad

AU - Ghori, Muhammad Usman

AU - Conway, Barbara

N1 - Conference code: 8

PY - 2017/12/4

Y1 - 2017/12/4

N2 - The aim of the present investigation was to understand the swelling behaviour of HPMC and PEO-based matrices and to evaluate the impact of porosity on the swelling kinetics. It was noticed that the HPMC has higher swelling rates but both undergo diffusion oriented swelling mechanism. It could also the concluded that the porosity has a marked influence in the development of gel layer on the surface of these matrices.

AB - The aim of the present investigation was to understand the swelling behaviour of HPMC and PEO-based matrices and to evaluate the impact of porosity on the swelling kinetics. It was noticed that the HPMC has higher swelling rates but both undergo diffusion oriented swelling mechanism. It could also the concluded that the porosity has a marked influence in the development of gel layer on the surface of these matrices.

KW - matrix tablet

KW - porosity

KW - swelling

KW - compaction

U2 - 10.5920/bjpharm.2017.16

DO - 10.5920/bjpharm.2017.16

M3 - Conference article

VL - 2

SP - S11-S13

JO - British Journal of Pharmacy

JF - British Journal of Pharmacy

SN - 2058-8356

IS - 2

T2 - 8th Academy of Pharmaceutical Science International PharmSci Conference

Y2 - 5 September 2017 through 7 September 2017

ER -

Probing the impact of porosity on swelling kinetics of hydrophilic matrices

Abstract

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