Abstract
HPMC and PEO-based matrices and to evaluate the impact of porosity on the
swelling kinetics. It was noticed that the HPMC has higher swelling rates but both
undergo diffusion oriented swelling mechanism. It could also the concluded that the
porosity has a marked influence in the development of gel layer on the surface of
these matrices.
| Original language | English |
|---|---|
| Pages (from-to) | S11-S13 |
| Number of pages | 3 |
| Journal | British Journal of Pharmacy |
| Volume | 2 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 4 Dec 2017 |
| Event | 8th Academy of Pharmaceutical Science International PharmSci Conference: Pharmaceutical Science Without Borders - University of Hertfordshire, Hatfield, United Kingdom Duration: 5 Sep 2017 → 7 Sep 2017 Conference number: 8 https://www.apsgb.co.uk/blog/Default.asp?D_A=20161101 (Link to Conference Information) |
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Probing the impact of porosity on swelling kinetics of hydrophilic matrices. / Asim, Muhammad; Ghori, Muhammad Usman ; Conway, Barbara.
In: British Journal of Pharmacy, Vol. 2, No. 2, 04.12.2017, p. S11-S13.Research output: Contribution to journal › Conference article
TY - JOUR
T1 - Probing the impact of porosity on swelling kinetics of hydrophilic matrices
AU - Asim, Muhammad
AU - Ghori, Muhammad Usman
AU - Conway, Barbara
PY - 2017/12/4
Y1 - 2017/12/4
N2 - The aim of the present investigation was to understand the swelling behaviour ofHPMC and PEO-based matrices and to evaluate the impact of porosity on theswelling kinetics. It was noticed that the HPMC has higher swelling rates but bothundergo diffusion oriented swelling mechanism. It could also the concluded that theporosity has a marked influence in the development of gel layer on the surface ofthese matrices.
AB - The aim of the present investigation was to understand the swelling behaviour ofHPMC and PEO-based matrices and to evaluate the impact of porosity on theswelling kinetics. It was noticed that the HPMC has higher swelling rates but bothundergo diffusion oriented swelling mechanism. It could also the concluded that theporosity has a marked influence in the development of gel layer on the surface ofthese matrices.
KW - matrix tablet
KW - porosity
KW - swelling
KW - compaction
U2 - 10.5920/bjpharm.2017.16
DO - 10.5920/bjpharm.2017.16
M3 - Conference article
VL - 2
SP - S11-S13
JO - British Journal of Pharmacy
JF - British Journal of Pharmacy
SN - 2058-8356
IS - 2
ER -