Probing the impact of porosity on swelling kinetics of hydrophilic matrices

Research output: Contribution to journalConference article

Abstract

The aim of the present investigation was to understand the swelling behaviour of
HPMC and PEO-based matrices and to evaluate the impact of porosity on the
swelling kinetics. It was noticed that the HPMC has higher swelling rates but both
undergo diffusion oriented swelling mechanism. It could also the concluded that the
porosity has a marked influence in the development of gel layer on the surface of
these matrices.
Original languageEnglish
Pages (from-to)S11-S13
Number of pages3
JournalBritish Journal of Pharmacy
Volume2
Issue number2
DOIs
Publication statusPublished - 4 Dec 2017
Event8th Academy of Pharmaceutical Science International PharmSci Conference: Pharmaceutical Science Without Borders - University of Hertfordshire, Hatfield, United Kingdom
Duration: 5 Sep 20177 Sep 2017
Conference number: 8
https://www.apsgb.co.uk/blog/Default.asp?D_A=20161101 (Link to Conference Information)

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title = "Probing the impact of porosity on swelling kinetics of hydrophilic matrices",
abstract = "The aim of the present investigation was to understand the swelling behaviour ofHPMC and PEO-based matrices and to evaluate the impact of porosity on theswelling kinetics. It was noticed that the HPMC has higher swelling rates but bothundergo diffusion oriented swelling mechanism. It could also the concluded that theporosity has a marked influence in the development of gel layer on the surface ofthese matrices.",
keywords = "matrix tablet, porosity, swelling, compaction",
author = "Muhammad Asim and Ghori, {Muhammad Usman} and Barbara Conway",
year = "2017",
month = "12",
day = "4",
doi = "10.5920/bjpharm.2017.16",
language = "English",
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pages = "S11--S13",
journal = "British Journal of Pharmacy",
issn = "2058-8356",
publisher = "University of Huddersfield Press",
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Probing the impact of porosity on swelling kinetics of hydrophilic matrices. / Asim, Muhammad; Ghori, Muhammad Usman ; Conway, Barbara.

In: British Journal of Pharmacy, Vol. 2, No. 2, 04.12.2017, p. S11-S13.

Research output: Contribution to journalConference article

TY - JOUR

T1 - Probing the impact of porosity on swelling kinetics of hydrophilic matrices

AU - Asim, Muhammad

AU - Ghori, Muhammad Usman

AU - Conway, Barbara

PY - 2017/12/4

Y1 - 2017/12/4

N2 - The aim of the present investigation was to understand the swelling behaviour ofHPMC and PEO-based matrices and to evaluate the impact of porosity on theswelling kinetics. It was noticed that the HPMC has higher swelling rates but bothundergo diffusion oriented swelling mechanism. It could also the concluded that theporosity has a marked influence in the development of gel layer on the surface ofthese matrices.

AB - The aim of the present investigation was to understand the swelling behaviour ofHPMC and PEO-based matrices and to evaluate the impact of porosity on theswelling kinetics. It was noticed that the HPMC has higher swelling rates but bothundergo diffusion oriented swelling mechanism. It could also the concluded that theporosity has a marked influence in the development of gel layer on the surface ofthese matrices.

KW - matrix tablet

KW - porosity

KW - swelling

KW - compaction

U2 - 10.5920/bjpharm.2017.16

DO - 10.5920/bjpharm.2017.16

M3 - Conference article

VL - 2

SP - S11-S13

JO - British Journal of Pharmacy

JF - British Journal of Pharmacy

SN - 2058-8356

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ER -