Progress in low-field benchtop NMR spectroscopy in chemical and biochemical analysis

Martin Grootveld, Benita Percival, Miles Gibson, Yasan Osman, Mark Edgar, Marco Molinari, Melissa L. Mather, Federico Casanova, Philippe B. Wilson

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

The employment of spectroscopically-resolved NMR techniques as analytical probes have previously been both prohibitively expensive and logistically challenging in view of the large sizes of high-field facilities. However, with recent advances in the miniaturisation of magnetic resonance technology, low-field, cryogen-free “benchtop” NMR instruments are seeing wider use. Indeed, these miniaturised spectrometers are utilised in areas ranging from food and agricultural analyses, through to human biofluid assays and disease monitoring. Therefore, it is both intrinsically timely and important to highlight current applications of this analytical strategy, and also provide an outlook for the future, where this approach may be applied to a wider range of analytical problems, both qualitatively and quantitatively.

Original languageEnglish
Pages (from-to)11-30
Number of pages20
JournalAnalytica Chimica Acta
Volume1067
Early online date23 Feb 2019
DOIs
Publication statusPublished - 27 Aug 2019

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