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Prospects for bioreductive drug development
R M Phillips
University of Bradford
Research output
:
Contribution to journal
›
Review article
›
peer-review
11
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Citations (Scopus)
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Keyphrases
Drug Development
100%
Bioreductant
100%
Tumor Hypoxia
25%
Aerobic
25%
Reductase
25%
Nitroimidazole
25%
Tumor
12%
Cisplatin
12%
Tumor Subtype
12%
Tirapazamine
12%
Prodrug
12%
Synergistic Effect
12%
Drug Delivery
12%
Active Substances
12%
Activation Mechanism
12%
Low Oxygen
12%
Proliferating Cells
12%
Further Development
12%
Clinical Activity
12%
Solid Tumors
12%
Hypoxic Zone
12%
Mitomycin C
12%
Hypoxia Markers
12%
Clinical Application
12%
Flow Effect
12%
Photodynamic Therapy
12%
Biological Basis
12%
Drug Therapy
12%
Invasive Procedures
12%
Preclinical Evaluation
12%
Promoter Sequence
12%
Drug Action
12%
Gene-directed Enzyme Prodrug Therapy (GDEPT)
12%
Cytotoxin
12%
Hypoxia-responsive
12%
Therapy Strategy
12%
Improved Properties
12%
Clinic Development
12%
Nitric Oxide Synthase Inhibitors
12%
Drug Strategy
12%
Tumor Blood Flow
12%
Oxygen Tension
12%
Prodrug-activating Enzyme
12%
Cell Activation
12%
Pharmacology, Toxicology and Pharmaceutical Science
Hypoxia
100%
Drug Development
100%
Prodrug
50%
Cisplatin
25%
Tirapazamine
25%
Oxidoreductase
25%
Solid Malignant Neoplasm
25%
Mitomycin
25%
Pharmacotherapy
25%
Photodynamic Therapy
25%
Cytotoxin
25%
Nitroimidazole
25%
Nitric Oxide Synthase
25%
Nitroimidazole Derivative
25%
Enzyme Prodrug Therapy
25%