Protein-like Oligomerization of Carbohydrates

Thomas Heinze, Melanie Nikolajski, Stephan Daus, Tabot M D Besong, Nico Michaelis, Peter Berlin, Gordon A. Morris, Arthur J. Rowe, Stephen E. Harding

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Sugar can, too: Many proteins form noncovalent and thermodynamically reversible oligomers, which can dictate a protein's functionality. For the first time, the presence of multiple oligomeric forms is shown in a whole class of polymeric carbohydrates, the 6-deoxy-6-aminocelluloses, using analytical ultracentrifugation as a probe.

LanguageEnglish
Pages8602-8604
Number of pages3
JournalAngewandte Chemie - International Edition
Volume50
Issue number37
Early online date22 Jul 2011
DOIs
Publication statusPublished - 5 Sep 2011
Externally publishedYes

Fingerprint

Oligomerization
Carbohydrates
Proteins
Oligomers
Sugars
Ultracentrifugation
6-amino-6-deoxycellulose

Cite this

Heinze, T., Nikolajski, M., Daus, S., Besong, T. M. D., Michaelis, N., Berlin, P., ... Harding, S. E. (2011). Protein-like Oligomerization of Carbohydrates. Angewandte Chemie - International Edition, 50(37), 8602-8604. https://doi.org/10.1002/anie.201103026
Heinze, Thomas ; Nikolajski, Melanie ; Daus, Stephan ; Besong, Tabot M D ; Michaelis, Nico ; Berlin, Peter ; Morris, Gordon A. ; Rowe, Arthur J. ; Harding, Stephen E. / Protein-like Oligomerization of Carbohydrates. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 37. pp. 8602-8604.
@article{5b3d9cb95ef84412a65a28a8ad4525be,
title = "Protein-like Oligomerization of Carbohydrates",
abstract = "Sugar can, too: Many proteins form noncovalent and thermodynamically reversible oligomers, which can dictate a protein's functionality. For the first time, the presence of multiple oligomeric forms is shown in a whole class of polymeric carbohydrates, the 6-deoxy-6-aminocelluloses, using analytical ultracentrifugation as a probe.",
keywords = "Aminocellulose, Analytical ultracentrifugation, Carbohydrates, Nanobiotechnology, Self-assembly",
author = "Thomas Heinze and Melanie Nikolajski and Stephan Daus and Besong, {Tabot M D} and Nico Michaelis and Peter Berlin and Morris, {Gordon A.} and Rowe, {Arthur J.} and Harding, {Stephen E.}",
year = "2011",
month = "9",
day = "5",
doi = "10.1002/anie.201103026",
language = "English",
volume = "50",
pages = "8602--8604",
journal = "Angewandte Chemie - International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "37",

}

Heinze, T, Nikolajski, M, Daus, S, Besong, TMD, Michaelis, N, Berlin, P, Morris, GA, Rowe, AJ & Harding, SE 2011, 'Protein-like Oligomerization of Carbohydrates', Angewandte Chemie - International Edition, vol. 50, no. 37, pp. 8602-8604. https://doi.org/10.1002/anie.201103026

Protein-like Oligomerization of Carbohydrates. / Heinze, Thomas; Nikolajski, Melanie; Daus, Stephan; Besong, Tabot M D; Michaelis, Nico; Berlin, Peter; Morris, Gordon A.; Rowe, Arthur J.; Harding, Stephen E.

In: Angewandte Chemie - International Edition, Vol. 50, No. 37, 05.09.2011, p. 8602-8604.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Protein-like Oligomerization of Carbohydrates

AU - Heinze, Thomas

AU - Nikolajski, Melanie

AU - Daus, Stephan

AU - Besong, Tabot M D

AU - Michaelis, Nico

AU - Berlin, Peter

AU - Morris, Gordon A.

AU - Rowe, Arthur J.

AU - Harding, Stephen E.

PY - 2011/9/5

Y1 - 2011/9/5

N2 - Sugar can, too: Many proteins form noncovalent and thermodynamically reversible oligomers, which can dictate a protein's functionality. For the first time, the presence of multiple oligomeric forms is shown in a whole class of polymeric carbohydrates, the 6-deoxy-6-aminocelluloses, using analytical ultracentrifugation as a probe.

AB - Sugar can, too: Many proteins form noncovalent and thermodynamically reversible oligomers, which can dictate a protein's functionality. For the first time, the presence of multiple oligomeric forms is shown in a whole class of polymeric carbohydrates, the 6-deoxy-6-aminocelluloses, using analytical ultracentrifugation as a probe.

KW - Aminocellulose

KW - Analytical ultracentrifugation

KW - Carbohydrates

KW - Nanobiotechnology

KW - Self-assembly

UR - http://www.scopus.com/inward/record.url?scp=80052471769&partnerID=8YFLogxK

UR - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773

U2 - 10.1002/anie.201103026

DO - 10.1002/anie.201103026

M3 - Article

VL - 50

SP - 8602

EP - 8604

JO - Angewandte Chemie - International Edition

T2 - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 37

ER -

Heinze T, Nikolajski M, Daus S, Besong TMD, Michaelis N, Berlin P et al. Protein-like Oligomerization of Carbohydrates. Angewandte Chemie - International Edition. 2011 Sep 5;50(37):8602-8604. https://doi.org/10.1002/anie.201103026