Quality versus Risk-of-Bias assessment in clinical research

Luis Furuya-Kanamori, Chang Xu, Syed Shahzad Hasan, Suhail A.R. Doi

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)


Assessment of internal validity safeguards implemented by researchers has been used to examine the potential reliability of evidence generated within a study. These safeguards protect against systematic error, and such an assessment has traditionally been called a quality assessment. When the results of a quality assessment are translated through some empirical construct to the potential risk of bias, this has been termed a risk of bias assessment. The latter has gained popularity and is commonly used interchangeably with the term quality assessment. This key concept paper clarifies the differences between these assessments and how they may be used and interpreted when assessing clinical evidence for internal validity.
Original languageEnglish
Pages (from-to)172-175
Number of pages4
JournalJournal of Clinical Epidemiology
Early online date6 Jan 2021
Publication statusPublished - 6 Jan 2021


Dive into the research topics of 'Quality versus Risk-of-Bias assessment in clinical research'. Together they form a unique fingerprint.

Cite this