Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages

P. A. Soares, F. Pereira, M. Brion, C. Alves, M. Richards, A. Carracedo, A. Amorim, L. Gusmão

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2 Citations (Scopus)


Y specific microsatellites (STRs) have been widely used in forensic and population genetics in age estimates of human male lineages. Previously, estimates of mutation rates from father-son pairs have given quite variable results in different studies, essentially due to the rarity of mutations. We propose an indirect approach for determining relative mutation rates of Y-chromosome microsatellites based on STR allele size intra-lineage variance. Indeed, the present distribution of STR alleles offers us an insight into the mechanisms that have generated that diversity.

Original languageEnglish
Pages (from-to)82-84
Number of pages3
JournalInternational Congress Series
Publication statusPublished - Apr 2006
Externally publishedYes


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