Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages

P. A. Soares, F. Pereira, M. Brion, C. Alves, M. Richards, A. Carracedo, A. Amorim, L. Gusmão

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Y specific microsatellites (STRs) have been widely used in forensic and population genetics in age estimates of human male lineages. Previously, estimates of mutation rates from father-son pairs have given quite variable results in different studies, essentially due to the rarity of mutations. We propose an indirect approach for determining relative mutation rates of Y-chromosome microsatellites based on STR allele size intra-lineage variance. Indeed, the present distribution of STR alleles offers us an insight into the mechanisms that have generated that diversity.

LanguageEnglish
Pages82-84
Number of pages3
JournalInternational Congress Series
Volume1288
DOIs
Publication statusPublished - Apr 2006
Externally publishedYes

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Mutation Rate
Microsatellite Repeats
Single Nucleotide Polymorphism
Forensic Genetics
Alleles
Y Chromosome
Population Genetics
Nuclear Family
Fathers
Mutation

Cite this

Soares, P. A. ; Pereira, F. ; Brion, M. ; Alves, C. ; Richards, M. ; Carracedo, A. ; Amorim, A. ; Gusmão, L. / Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages. In: International Congress Series. 2006 ; Vol. 1288. pp. 82-84.
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Soares, PA, Pereira, F, Brion, M, Alves, C, Richards, M, Carracedo, A, Amorim, A & Gusmão, L 2006, 'Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages', International Congress Series, vol. 1288, pp. 82-84. https://doi.org/10.1016/j.ics.2005.09.173

Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages. / Soares, P. A.; Pereira, F.; Brion, M.; Alves, C.; Richards, M.; Carracedo, A.; Amorim, A.; Gusmão, L.

In: International Congress Series, Vol. 1288, 04.2006, p. 82-84.

Research output: Contribution to journalArticle

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