South Yorkshire Cohort: a 'cohort trials facility' study of health and weight: Protocol for the recruitment phase

Clare Relton, Paul Bissell, Christine Smith, Joanna Blackburn, Cindy L Cooper, Jon Nicholl, Angela Tod, Rob Copeland, Amanda Loban, Tim Chater, Kate Thomas, Tracey Young, Carol Weir, Gill Harrison, Alison Milbourn, Rachel Manners

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background:
Growing levels of both obesity and chronic disease in the general population pose a major public health problem. In the UK, an innovative 'health and weight' cohort trials facility, the 'South Yorkshire Cohort', is being built in order to provide robust evidence to inform policy, commissioning and clinical decisions in this field. This protocol reports the design of the facility and outlines the recruitment phase methods.

Method/Design:
The South Yorkshire Cohort health and weight study uses the cohort multiple randomised controlled trial design. This design recruits a large observational cohort of patients with the condition(s) of interest which then provides a facility for multiple randomised controlled trials (with large representative samples of participants, long term outcomes as standard, increased comparability between each trial conducted within the cohort and increased efficiency particularly for trials of expensive interventions) as well as ongoing information as to the natural history of the condition and treatment as usual.

This study aims to recruit 20,000 participants to the population based South Yorkshire Cohort health and weight research trials facility. Participants are recruited by invitation letters from their General Practitioners. Data is collected using postal and/or online patient self completed Health Questionnaires. NHS numbers will be used to facilitate record linkage and access to routine data. Participants are eligible if they are: aged 16 - 85 years, registered with one of 40 practices in South Yorkshire, provide consent for further contact from the researchers and to have their information used to look at the benefit of health treatments. The first wave of data is being collected during 2010/12 and further waves are planned at 2 - 5 year intervals for the planned 20 year duration of the facility.

Discussion:
The South Yorkshire Cohort combines the strengths of the standard observational, longitudinal cohort study design with a population based cohort facility for multiple randomised controlled trials in a range of long term health and weight related conditions (including obesity). This infrastructure will allow the rapid and cheap identification and recruitment of patients, and facilitate the provision of robust evidence to inform the management and self-management of health and weight.
LanguageEnglish
Article number640
Number of pages9
JournalBMC Public Health
Volume11
DOIs
Publication statusPublished - 2011
Externally publishedYes

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Health Facilities
Weights and Measures
Health
Randomized Controlled Trials
Cohort Studies
Obesity
Facility Design and Construction
Population
Insurance Benefits
Self Care
Natural History
General Practitioners
Patient Selection
Longitudinal Studies
Chronic Disease
Public Health
Research Personnel
Therapeutics
Research

Cite this

Relton, Clare ; Bissell, Paul ; Smith, Christine ; Blackburn, Joanna ; Cooper, Cindy L ; Nicholl, Jon ; Tod, Angela ; Copeland, Rob ; Loban, Amanda ; Chater, Tim ; Thomas, Kate ; Young, Tracey ; Weir, Carol ; Harrison, Gill ; Milbourn, Alison ; Manners, Rachel. / South Yorkshire Cohort: a 'cohort trials facility' study of health and weight : Protocol for the recruitment phase. In: BMC Public Health. 2011 ; Vol. 11.
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title = "South Yorkshire Cohort: a 'cohort trials facility' study of health and weight: Protocol for the recruitment phase",
abstract = "Background:Growing levels of both obesity and chronic disease in the general population pose a major public health problem. In the UK, an innovative 'health and weight' cohort trials facility, the 'South Yorkshire Cohort', is being built in order to provide robust evidence to inform policy, commissioning and clinical decisions in this field. This protocol reports the design of the facility and outlines the recruitment phase methods.Method/Design:The South Yorkshire Cohort health and weight study uses the cohort multiple randomised controlled trial design. This design recruits a large observational cohort of patients with the condition(s) of interest which then provides a facility for multiple randomised controlled trials (with large representative samples of participants, long term outcomes as standard, increased comparability between each trial conducted within the cohort and increased efficiency particularly for trials of expensive interventions) as well as ongoing information as to the natural history of the condition and treatment as usual.This study aims to recruit 20,000 participants to the population based South Yorkshire Cohort health and weight research trials facility. Participants are recruited by invitation letters from their General Practitioners. Data is collected using postal and/or online patient self completed Health Questionnaires. NHS numbers will be used to facilitate record linkage and access to routine data. Participants are eligible if they are: aged 16 - 85 years, registered with one of 40 practices in South Yorkshire, provide consent for further contact from the researchers and to have their information used to look at the benefit of health treatments. The first wave of data is being collected during 2010/12 and further waves are planned at 2 - 5 year intervals for the planned 20 year duration of the facility.Discussion:The South Yorkshire Cohort combines the strengths of the standard observational, longitudinal cohort study design with a population based cohort facility for multiple randomised controlled trials in a range of long term health and weight related conditions (including obesity). This infrastructure will allow the rapid and cheap identification and recruitment of patients, and facilitate the provision of robust evidence to inform the management and self-management of health and weight.",
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Relton, C, Bissell, P, Smith, C, Blackburn, J, Cooper, CL, Nicholl, J, Tod, A, Copeland, R, Loban, A, Chater, T, Thomas, K, Young, T, Weir, C, Harrison, G, Milbourn, A & Manners, R 2011, 'South Yorkshire Cohort: a 'cohort trials facility' study of health and weight: Protocol for the recruitment phase', BMC Public Health, vol. 11, 640. https://doi.org/10.1186/1471-2458-11-640

South Yorkshire Cohort: a 'cohort trials facility' study of health and weight : Protocol for the recruitment phase. / Relton, Clare; Bissell, Paul; Smith, Christine; Blackburn, Joanna; Cooper, Cindy L; Nicholl, Jon; Tod, Angela; Copeland, Rob; Loban, Amanda; Chater, Tim; Thomas, Kate; Young, Tracey; Weir, Carol; Harrison, Gill; Milbourn, Alison; Manners, Rachel.

In: BMC Public Health, Vol. 11, 640, 2011.

Research output: Contribution to journalArticle

TY - JOUR

T1 - South Yorkshire Cohort: a 'cohort trials facility' study of health and weight

T2 - BMC Public Health

AU - Relton, Clare

AU - Bissell, Paul

AU - Smith, Christine

AU - Blackburn, Joanna

AU - Cooper, Cindy L

AU - Nicholl, Jon

AU - Tod, Angela

AU - Copeland, Rob

AU - Loban, Amanda

AU - Chater, Tim

AU - Thomas, Kate

AU - Young, Tracey

AU - Weir, Carol

AU - Harrison, Gill

AU - Milbourn, Alison

AU - Manners, Rachel

PY - 2011

Y1 - 2011

N2 - Background:Growing levels of both obesity and chronic disease in the general population pose a major public health problem. In the UK, an innovative 'health and weight' cohort trials facility, the 'South Yorkshire Cohort', is being built in order to provide robust evidence to inform policy, commissioning and clinical decisions in this field. This protocol reports the design of the facility and outlines the recruitment phase methods.Method/Design:The South Yorkshire Cohort health and weight study uses the cohort multiple randomised controlled trial design. This design recruits a large observational cohort of patients with the condition(s) of interest which then provides a facility for multiple randomised controlled trials (with large representative samples of participants, long term outcomes as standard, increased comparability between each trial conducted within the cohort and increased efficiency particularly for trials of expensive interventions) as well as ongoing information as to the natural history of the condition and treatment as usual.This study aims to recruit 20,000 participants to the population based South Yorkshire Cohort health and weight research trials facility. Participants are recruited by invitation letters from their General Practitioners. Data is collected using postal and/or online patient self completed Health Questionnaires. NHS numbers will be used to facilitate record linkage and access to routine data. Participants are eligible if they are: aged 16 - 85 years, registered with one of 40 practices in South Yorkshire, provide consent for further contact from the researchers and to have their information used to look at the benefit of health treatments. The first wave of data is being collected during 2010/12 and further waves are planned at 2 - 5 year intervals for the planned 20 year duration of the facility.Discussion:The South Yorkshire Cohort combines the strengths of the standard observational, longitudinal cohort study design with a population based cohort facility for multiple randomised controlled trials in a range of long term health and weight related conditions (including obesity). This infrastructure will allow the rapid and cheap identification and recruitment of patients, and facilitate the provision of robust evidence to inform the management and self-management of health and weight.

AB - Background:Growing levels of both obesity and chronic disease in the general population pose a major public health problem. In the UK, an innovative 'health and weight' cohort trials facility, the 'South Yorkshire Cohort', is being built in order to provide robust evidence to inform policy, commissioning and clinical decisions in this field. This protocol reports the design of the facility and outlines the recruitment phase methods.Method/Design:The South Yorkshire Cohort health and weight study uses the cohort multiple randomised controlled trial design. This design recruits a large observational cohort of patients with the condition(s) of interest which then provides a facility for multiple randomised controlled trials (with large representative samples of participants, long term outcomes as standard, increased comparability between each trial conducted within the cohort and increased efficiency particularly for trials of expensive interventions) as well as ongoing information as to the natural history of the condition and treatment as usual.This study aims to recruit 20,000 participants to the population based South Yorkshire Cohort health and weight research trials facility. Participants are recruited by invitation letters from their General Practitioners. Data is collected using postal and/or online patient self completed Health Questionnaires. NHS numbers will be used to facilitate record linkage and access to routine data. Participants are eligible if they are: aged 16 - 85 years, registered with one of 40 practices in South Yorkshire, provide consent for further contact from the researchers and to have their information used to look at the benefit of health treatments. The first wave of data is being collected during 2010/12 and further waves are planned at 2 - 5 year intervals for the planned 20 year duration of the facility.Discussion:The South Yorkshire Cohort combines the strengths of the standard observational, longitudinal cohort study design with a population based cohort facility for multiple randomised controlled trials in a range of long term health and weight related conditions (including obesity). This infrastructure will allow the rapid and cheap identification and recruitment of patients, and facilitate the provision of robust evidence to inform the management and self-management of health and weight.

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