Studies on the anti-inflammatory properties of Entada abyssinica

O. A. Olajide; A. R.A. Alada

doi:10.1016/S0367-326X(01)00273-8

Studies on the anti-inflammatory properties of Entada abyssinica

O. A. Olajide, A. R.A. Alada

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The defatted methanolic extract of Entada abyssinica was evaluated for anti-inflammatory activity in acute and chronic models of inflammation. The extract (50-200 mg/kg, p.o.) exhibited dose-dependent and significant inhibition of both the carrageenan-induced rat paw oedema and granuloma tissue formation in rats. The extract (50-200 mg/kg, p.o.) was also found to inhibit the acetic acid-induced vascular permeability in a dose-dependent fashion in mice. This study demonstrated the anti-inflammatory activity of Entada abyssinica.

Original language	English
Pages (from-to)	492-496
Number of pages	5
Journal	Fitoterapia
Volume	72
Issue number	5
DOIs	https://doi.org/10.1016/S0367-326X(01)00273-8
Publication status	Published - 21 Jun 2001
Externally published	Yes

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10.1016/S0367-326X(01)00273-8

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AB - The defatted methanolic extract of Entada abyssinica was evaluated for anti-inflammatory activity in acute and chronic models of inflammation. The extract (50-200 mg/kg, p.o.) exhibited dose-dependent and significant inhibition of both the carrageenan-induced rat paw oedema and granuloma tissue formation in rats. The extract (50-200 mg/kg, p.o.) was also found to inhibit the acetic acid-induced vascular permeability in a dose-dependent fashion in mice. This study demonstrated the anti-inflammatory activity of Entada abyssinica.

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Studies on the anti-inflammatory properties of Entada abyssinica

Abstract

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