Studies on the anti-inflammatory properties of Entada abyssinica

O. A. Olajide, A. R.A. Alada

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The defatted methanolic extract of Entada abyssinica was evaluated for anti-inflammatory activity in acute and chronic models of inflammation. The extract (50-200 mg/kg, p.o.) exhibited dose-dependent and significant inhibition of both the carrageenan-induced rat paw oedema and granuloma tissue formation in rats. The extract (50-200 mg/kg, p.o.) was also found to inhibit the acetic acid-induced vascular permeability in a dose-dependent fashion in mice. This study demonstrated the anti-inflammatory activity of Entada abyssinica.

Original languageEnglish
Pages (from-to)492-496
Number of pages5
JournalFitoterapia
Volume72
Issue number5
DOIs
Publication statusPublished - 21 Jun 2001
Externally publishedYes

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