Abstract
The defatted methanolic extract of Entada abyssinica was evaluated for anti-inflammatory activity in acute and chronic models of inflammation. The extract (50-200 mg/kg, p.o.) exhibited dose-dependent and significant inhibition of both the carrageenan-induced rat paw oedema and granuloma tissue formation in rats. The extract (50-200 mg/kg, p.o.) was also found to inhibit the acetic acid-induced vascular permeability in a dose-dependent fashion in mice. This study demonstrated the anti-inflammatory activity of Entada abyssinica.
| Original language | English |
|---|---|
| Pages (from-to) | 492-496 |
| Number of pages | 5 |
| Journal | Fitoterapia |
| Volume | 72 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 21 Jun 2001 |
| Externally published | Yes |