Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells

Muhammad Mahadi Abdul Jamil; Nur Adilah Abd Rahman; Mohd Nazib Adon; Radzi Ambar; Farideh Javid; Mansour Youseffi; Syafiqah Saidin

doi:10.1109/CSPA57446.2023.10087551

Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells

Muhammad Mahadi Abdul Jamil, Nur Adilah Abd Rahman, Mohd Nazib Adon, Radzi Ambar, Farideh Javid, Mansour Youseffi, Syafiqah Saidin

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Discovering a new cancer treatment Researchers are becoming more eager to uncover new medicinal compounds from living species. In the UK, CBD has been rising in demand as an alternative therapeutic agent and is used in various medicinal products. CBD, or cannabidiol, is a phytocannabinoid, one of the identified cannabinoids in cannabis plants. It doesn't contain tetrahydrocannabinol (THC), which is a psychoactive ingredient. While electroporation is one of the non-invasive techniques for nonviral delivery systems, such as molecule introduction and molecule transfer in a variety of sizes depending on the parameter chosen. The cell response to CBD compound combined with the electroporation method was the focus of this study. The findings demonstrated a positive response to the antiproliferative properties of cancer cells, and the treatment was further aided by a pulse electric field of 600 V/cm for 30 \mu \mathrm{s} with a single pulse. The results showed further decrements in cell viability. This finding may contribute toward cancer treatment as an adjunct alternative anticancer agent.

Original language	English
Title of host publication	2023 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 - Conference Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	283-286
Number of pages	4
ISBN (Electronic)	9781665476928, 9781665476911
ISBN (Print)	9781665476935
DOIs	https://doi.org/10.1109/CSPA57446.2023.10087551
Publication status	Published - 5 Apr 2023
Event	19th IEEE International Colloquium on Signal Processing and Its Applications - Kedah, Malaysia Duration: 3 Mar 2023 → 4 Mar 2023 Conference number: 19

Conference

Conference	19th IEEE International Colloquium on Signal Processing and Its Applications
Abbreviated title	CSPA 2023
Country/Territory	Malaysia
City	Kedah
Period	3/03/23 → 4/03/23

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Jamil, M. M. A., Rahman, N. A. A., Adon, M. N., Ambar, R., Javid, F., Youseffi, M., & Saidin, S. (2023). Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells. In 2023 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 - Conference Proceedings (pp. 283-286). [10087551] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CSPA57446.2023.10087551

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title = "Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells",

abstract = "Discovering a new cancer treatment Researchers are becoming more eager to uncover new medicinal compounds from living species. In the UK, CBD has been rising in demand as an alternative therapeutic agent and is used in various medicinal products. CBD, or cannabidiol, is a phytocannabinoid, one of the identified cannabinoids in cannabis plants. It doesn't contain tetrahydrocannabinol (THC), which is a psychoactive ingredient. While electroporation is one of the non-invasive techniques for nonviral delivery systems, such as molecule introduction and molecule transfer in a variety of sizes depending on the parameter chosen. The cell response to CBD compound combined with the electroporation method was the focus of this study. The findings demonstrated a positive response to the antiproliferative properties of cancer cells, and the treatment was further aided by a pulse electric field of 600 V/cm for 30 \mu \mathrm{s} with a single pulse. The results showed further decrements in cell viability. This finding may contribute toward cancer treatment as an adjunct alternative anticancer agent.",

keywords = "Breast cancer cell, CBD, electroporation, therapeutic",

author = "Jamil, {Muhammad Mahadi Abdul} and Rahman, {Nur Adilah Abd} and Adon, {Mohd Nazib} and Radzi Ambar and Farideh Javid and Mansour Youseffi and Syafiqah Saidin",

note = "Funding Information: ACKNOWLEDGMENT This research was supported by the Ministry of Higher Education (MOHE) through Fundamental Research Grant Scheme (FRGS) (FRGS/1/2020/TK0/UTHM/02/23) and Universiti Tun Hussein Onn Malaysia (UTHM) Vot: K304. Publisher Copyright: {\textcopyright} 2023 IEEE.; 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 ; Conference date: 03-03-2023 Through 04-03-2023",

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doi = "10.1109/CSPA57446.2023.10087551",

language = "English",

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Jamil, MMA, Rahman, NAA, Adon, MN, Ambar, R, Javid, F, Youseffi, M & Saidin, S 2023, Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells. in 2023 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 - Conference Proceedings., 10087551, Institute of Electrical and Electronics Engineers Inc., pp. 283-286, 19th IEEE International Colloquium on Signal Processing and Its Applications, Kedah, Malaysia, 3/03/23. https://doi.org/10.1109/CSPA57446.2023.10087551

Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells. / Jamil, Muhammad Mahadi Abdul; Rahman, Nur Adilah Abd; Adon, Mohd Nazib et al.

2023 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2023. p. 283-286 10087551.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells

AU - Jamil, Muhammad Mahadi Abdul

AU - Rahman, Nur Adilah Abd

AU - Adon, Mohd Nazib

AU - Ambar, Radzi

AU - Javid, Farideh

AU - Youseffi, Mansour

AU - Saidin, Syafiqah

N1 - Conference code: 19

PY - 2023/4/5

Y1 - 2023/4/5

N2 - Discovering a new cancer treatment Researchers are becoming more eager to uncover new medicinal compounds from living species. In the UK, CBD has been rising in demand as an alternative therapeutic agent and is used in various medicinal products. CBD, or cannabidiol, is a phytocannabinoid, one of the identified cannabinoids in cannabis plants. It doesn't contain tetrahydrocannabinol (THC), which is a psychoactive ingredient. While electroporation is one of the non-invasive techniques for nonviral delivery systems, such as molecule introduction and molecule transfer in a variety of sizes depending on the parameter chosen. The cell response to CBD compound combined with the electroporation method was the focus of this study. The findings demonstrated a positive response to the antiproliferative properties of cancer cells, and the treatment was further aided by a pulse electric field of 600 V/cm for 30 \mu \mathrm{s} with a single pulse. The results showed further decrements in cell viability. This finding may contribute toward cancer treatment as an adjunct alternative anticancer agent.

AB - Discovering a new cancer treatment Researchers are becoming more eager to uncover new medicinal compounds from living species. In the UK, CBD has been rising in demand as an alternative therapeutic agent and is used in various medicinal products. CBD, or cannabidiol, is a phytocannabinoid, one of the identified cannabinoids in cannabis plants. It doesn't contain tetrahydrocannabinol (THC), which is a psychoactive ingredient. While electroporation is one of the non-invasive techniques for nonviral delivery systems, such as molecule introduction and molecule transfer in a variety of sizes depending on the parameter chosen. The cell response to CBD compound combined with the electroporation method was the focus of this study. The findings demonstrated a positive response to the antiproliferative properties of cancer cells, and the treatment was further aided by a pulse electric field of 600 V/cm for 30 \mu \mathrm{s} with a single pulse. The results showed further decrements in cell viability. This finding may contribute toward cancer treatment as an adjunct alternative anticancer agent.

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DO - 10.1109/CSPA57446.2023.10087551

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SN - 9781665476935

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BT - 2023 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 - Conference Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

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Y2 - 3 March 2023 through 4 March 2023

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Jamil MMA, Rahman NAA, Adon MN, Ambar R, Javid F, Youseffi M et al. Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells. In 2023 19th IEEE International Colloquium on Signal Processing and Its Applications, CSPA 2023 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc. 2023. p. 283-286. 10087551 doi: 10.1109/CSPA57446.2023.10087551

Study on Cannabidiol and Pulse Electric Field on Breast Cancer Cells

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