Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove

Ojan Assadian, Axel Kramer, Kenneth Ouriel, Miranda Suchomel, Mary Louise McLaws, Martin Rottman, David Leaper, Afshin Assadian

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background: Perforations of surgical gloves are common and increase with the duration of glove wear. Skin flora, re-grown after pre-operative disinfection of the hands, may contaminate a surgical site. An antimicrobial surgical glove with chlorhexidine on its inner surface has been developed. We hypothesized that by suppressing the re-growth of skin flora during the complete course of a surgical procedure, antimicrobial gloves may reduce the risk of surgical site contamination in the event of an intra-operative glove breach. Methods: We conducted a randomized, double-blind, single-center trial, to measure any differences in the bacterial skin populations of surgeons' hands during surgical procedures done with antimicrobial and non-antimicrobial surgical gloves [ISRCTN71391952]. In this study, 25 pairs of gloves were retrieved from 14 surgeons who donned them randomly on their dominant or non-dominant hand. The number of bacteria retrieved from glove fluid was measured and expressed as colony forming units (CFU)/mL. Results: The median cfu/mL of antimicrobial gloves was 0.00 (LQ: 0.00 CFU/mL; UQ: 0.00 cfu/mL), with a mean log10 cfu/mL=0.02 (range: 0.00-0.30). The median CFU/mL of non-antimicrobial gloves was 54.00 (LQ: 3.00 cfu/mL; UQ: 100.00 cfu/mL) with a mean log10 CFU/mL=1.32 (range: 0.00-2.39). After a mean operating time of 112 min, the difference in the log10 CFU/mL was 1.30 (p<0.001). Conclusions: A new antimicrobial surgical glove suppressed surgeons' hand flora during operative procedures. In the event of a glove breach, the use of such a glove may have the potential to prevent bacterial contamination of a sterile surgical site, thereby decreasing the risk of surgical site infection (SSI) and increasing patient safety. Further clinical studies are needed to confirm this concept.

Original languageEnglish
Pages (from-to)43-49
Number of pages7
JournalSurgical Infections
Volume15
Issue number1
Early online date12 Oct 2013
DOIs
Publication statusPublished - 7 Feb 2014
Externally publishedYes

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Surgical Gloves
Stem Cells
Hand
Skin
Surgical Wound Infection
Hand Disinfection
Chlorhexidine
Operative Surgical Procedures
Patient Safety
Surgeons
Bacteria
Growth
Population

Cite this

Assadian, O., Kramer, A., Ouriel, K., Suchomel, M., McLaws, M. L., Rottman, M., ... Assadian, A. (2014). Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove. Surgical Infections, 15(1), 43-49. https://doi.org/10.1089/sur.2012.230
Assadian, Ojan ; Kramer, Axel ; Ouriel, Kenneth ; Suchomel, Miranda ; McLaws, Mary Louise ; Rottman, Martin ; Leaper, David ; Assadian, Afshin. / Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove. In: Surgical Infections. 2014 ; Vol. 15, No. 1. pp. 43-49.
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abstract = "Background: Perforations of surgical gloves are common and increase with the duration of glove wear. Skin flora, re-grown after pre-operative disinfection of the hands, may contaminate a surgical site. An antimicrobial surgical glove with chlorhexidine on its inner surface has been developed. We hypothesized that by suppressing the re-growth of skin flora during the complete course of a surgical procedure, antimicrobial gloves may reduce the risk of surgical site contamination in the event of an intra-operative glove breach. Methods: We conducted a randomized, double-blind, single-center trial, to measure any differences in the bacterial skin populations of surgeons' hands during surgical procedures done with antimicrobial and non-antimicrobial surgical gloves [ISRCTN71391952]. In this study, 25 pairs of gloves were retrieved from 14 surgeons who donned them randomly on their dominant or non-dominant hand. The number of bacteria retrieved from glove fluid was measured and expressed as colony forming units (CFU)/mL. Results: The median cfu/mL of antimicrobial gloves was 0.00 (LQ: 0.00 CFU/mL; UQ: 0.00 cfu/mL), with a mean log10 cfu/mL=0.02 (range: 0.00-0.30). The median CFU/mL of non-antimicrobial gloves was 54.00 (LQ: 3.00 cfu/mL; UQ: 100.00 cfu/mL) with a mean log10 CFU/mL=1.32 (range: 0.00-2.39). After a mean operating time of 112 min, the difference in the log10 CFU/mL was 1.30 (p<0.001). Conclusions: A new antimicrobial surgical glove suppressed surgeons' hand flora during operative procedures. In the event of a glove breach, the use of such a glove may have the potential to prevent bacterial contamination of a sterile surgical site, thereby decreasing the risk of surgical site infection (SSI) and increasing patient safety. Further clinical studies are needed to confirm this concept.",
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Assadian, O, Kramer, A, Ouriel, K, Suchomel, M, McLaws, ML, Rottman, M, Leaper, D & Assadian, A 2014, 'Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove', Surgical Infections, vol. 15, no. 1, pp. 43-49. https://doi.org/10.1089/sur.2012.230

Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove. / Assadian, Ojan; Kramer, Axel; Ouriel, Kenneth; Suchomel, Miranda; McLaws, Mary Louise; Rottman, Martin; Leaper, David; Assadian, Afshin.

In: Surgical Infections, Vol. 15, No. 1, 07.02.2014, p. 43-49.

Research output: Contribution to journalArticle

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T1 - Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove

AU - Assadian, Ojan

AU - Kramer, Axel

AU - Ouriel, Kenneth

AU - Suchomel, Miranda

AU - McLaws, Mary Louise

AU - Rottman, Martin

AU - Leaper, David

AU - Assadian, Afshin

PY - 2014/2/7

Y1 - 2014/2/7

N2 - Background: Perforations of surgical gloves are common and increase with the duration of glove wear. Skin flora, re-grown after pre-operative disinfection of the hands, may contaminate a surgical site. An antimicrobial surgical glove with chlorhexidine on its inner surface has been developed. We hypothesized that by suppressing the re-growth of skin flora during the complete course of a surgical procedure, antimicrobial gloves may reduce the risk of surgical site contamination in the event of an intra-operative glove breach. Methods: We conducted a randomized, double-blind, single-center trial, to measure any differences in the bacterial skin populations of surgeons' hands during surgical procedures done with antimicrobial and non-antimicrobial surgical gloves [ISRCTN71391952]. In this study, 25 pairs of gloves were retrieved from 14 surgeons who donned them randomly on their dominant or non-dominant hand. The number of bacteria retrieved from glove fluid was measured and expressed as colony forming units (CFU)/mL. Results: The median cfu/mL of antimicrobial gloves was 0.00 (LQ: 0.00 CFU/mL; UQ: 0.00 cfu/mL), with a mean log10 cfu/mL=0.02 (range: 0.00-0.30). The median CFU/mL of non-antimicrobial gloves was 54.00 (LQ: 3.00 cfu/mL; UQ: 100.00 cfu/mL) with a mean log10 CFU/mL=1.32 (range: 0.00-2.39). After a mean operating time of 112 min, the difference in the log10 CFU/mL was 1.30 (p<0.001). Conclusions: A new antimicrobial surgical glove suppressed surgeons' hand flora during operative procedures. In the event of a glove breach, the use of such a glove may have the potential to prevent bacterial contamination of a sterile surgical site, thereby decreasing the risk of surgical site infection (SSI) and increasing patient safety. Further clinical studies are needed to confirm this concept.

AB - Background: Perforations of surgical gloves are common and increase with the duration of glove wear. Skin flora, re-grown after pre-operative disinfection of the hands, may contaminate a surgical site. An antimicrobial surgical glove with chlorhexidine on its inner surface has been developed. We hypothesized that by suppressing the re-growth of skin flora during the complete course of a surgical procedure, antimicrobial gloves may reduce the risk of surgical site contamination in the event of an intra-operative glove breach. Methods: We conducted a randomized, double-blind, single-center trial, to measure any differences in the bacterial skin populations of surgeons' hands during surgical procedures done with antimicrobial and non-antimicrobial surgical gloves [ISRCTN71391952]. In this study, 25 pairs of gloves were retrieved from 14 surgeons who donned them randomly on their dominant or non-dominant hand. The number of bacteria retrieved from glove fluid was measured and expressed as colony forming units (CFU)/mL. Results: The median cfu/mL of antimicrobial gloves was 0.00 (LQ: 0.00 CFU/mL; UQ: 0.00 cfu/mL), with a mean log10 cfu/mL=0.02 (range: 0.00-0.30). The median CFU/mL of non-antimicrobial gloves was 54.00 (LQ: 3.00 cfu/mL; UQ: 100.00 cfu/mL) with a mean log10 CFU/mL=1.32 (range: 0.00-2.39). After a mean operating time of 112 min, the difference in the log10 CFU/mL was 1.30 (p<0.001). Conclusions: A new antimicrobial surgical glove suppressed surgeons' hand flora during operative procedures. In the event of a glove breach, the use of such a glove may have the potential to prevent bacterial contamination of a sterile surgical site, thereby decreasing the risk of surgical site infection (SSI) and increasing patient safety. Further clinical studies are needed to confirm this concept.

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U2 - 10.1089/sur.2012.230

DO - 10.1089/sur.2012.230

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JF - Surgical Infections

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