Abstract
Novel chiral analogues of the antioxidant, anti‐inflammatory organoselenium drug ebselen were synthesized. The reaction proceeded readily from 2‐(chloroseleno)benzoyl chloride with chiral amino compounds. The chiral substituent on the nitrogen atom did not provide a substantial increase in activities and the newly synthesized compounds showed similar activities to ebselen.
Original language | English |
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Pages (from-to) | 320-325 |
Number of pages | 6 |
Journal | Heteroatom Chemistry |
Volume | 25 |
Issue number | 5 |
Early online date | 9 May 2014 |
DOIs | |
Publication status | Published - 1 Nov 2014 |
Externally published | Yes |