Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands

Quan Tang, Wen Xiu Ni, Chi Fai Leung, Wai Lun Man, Kenneth King Kwan Lau, Yimin Liang, Yun Wah Lam, Wai Yeung Wong, Shie Ming Peng, Gui Jian Liu, Tai Chu Lau

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33 Citations (Scopus)


A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

Original languageEnglish
Pages (from-to)9980-9982
Number of pages3
JournalChemical Communications
Issue number85
Early online date28 Aug 2013
Publication statusPublished - 4 Nov 2013
Externally publishedYes

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