Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands

Quan Tang, Wen Xiu Ni, Chi Fai Leung, Wai Lun Man, Kenneth King Kwan Lau, Yimin Liang, Yun Wah Lam, Wai Yeung Wong, Shie Ming Peng, Gui Jian Liu, Tai Chu Lau

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

Original languageEnglish
Pages (from-to)9980-9982
Number of pages3
JournalChemical Communications
Volume49
Issue number85
Early online date28 Aug 2013
DOIs
Publication statusPublished - 4 Nov 2013
Externally publishedYes

Cite this