Synthesis of densely functionalised arenes using [2 + 2 + 2] cycloaddition reactions

Jonathan Clayden, Wesley J. Moran

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Rh(I)-catalysed [2 + 2 + 2] cycloaddition allows the synthesis of aryl ethers and diaryl methanes containing a high degree of steric hindrance from relatively simple diyne and alkyne precursors. The diarylmethanes made in this way show no evidence in their NMR spectra, however, of rotational restriction.

LanguageEnglish
Pages1028-1030
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number7
Early online date27 Feb 2007
DOIs
Publication statusPublished - 7 Apr 2007
Externally publishedYes

Fingerprint

Alkynes
Ethers
Cycloaddition
Methane
Cycloaddition Reaction
cycloaddition
alkynes
ethers
constrictions
methane
Nuclear magnetic resonance
nuclear magnetic resonance
synthesis

Cite this

@article{92cfc4c408d443bdb6d5a4fc63b047b2,
title = "Synthesis of densely functionalised arenes using [2 + 2 + 2] cycloaddition reactions",
abstract = "Rh(I)-catalysed [2 + 2 + 2] cycloaddition allows the synthesis of aryl ethers and diaryl methanes containing a high degree of steric hindrance from relatively simple diyne and alkyne precursors. The diarylmethanes made in this way show no evidence in their NMR spectra, however, of rotational restriction.",
author = "Jonathan Clayden and Moran, {Wesley J.}",
year = "2007",
month = "4",
day = "7",
doi = "10.1039/b700353f",
language = "English",
volume = "5",
pages = "1028--1030",
journal = "Organic and Biomolecular Chemistry",
issn = "1477-0520",
publisher = "Royal Society of Chemistry",
number = "7",

}

Synthesis of densely functionalised arenes using [2 + 2 + 2] cycloaddition reactions. / Clayden, Jonathan; Moran, Wesley J.

In: Organic and Biomolecular Chemistry, Vol. 5, No. 7, 07.04.2007, p. 1028-1030.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthesis of densely functionalised arenes using [2 + 2 + 2] cycloaddition reactions

AU - Clayden, Jonathan

AU - Moran, Wesley J.

PY - 2007/4/7

Y1 - 2007/4/7

N2 - Rh(I)-catalysed [2 + 2 + 2] cycloaddition allows the synthesis of aryl ethers and diaryl methanes containing a high degree of steric hindrance from relatively simple diyne and alkyne precursors. The diarylmethanes made in this way show no evidence in their NMR spectra, however, of rotational restriction.

AB - Rh(I)-catalysed [2 + 2 + 2] cycloaddition allows the synthesis of aryl ethers and diaryl methanes containing a high degree of steric hindrance from relatively simple diyne and alkyne precursors. The diarylmethanes made in this way show no evidence in their NMR spectra, however, of rotational restriction.

UR - http://www.scopus.com/inward/record.url?scp=33947504847&partnerID=8YFLogxK

U2 - 10.1039/b700353f

DO - 10.1039/b700353f

M3 - Article

VL - 5

SP - 1028

EP - 1030

JO - Organic and Biomolecular Chemistry

T2 - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 7

ER -