Abstract
Several Ru-arene and Ir-Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.
| Original language | English |
|---|---|
| Pages (from-to) | 13800-13802 |
| Number of pages | 3 |
| Journal | Dalton Transactions |
| Volume | 41 |
| Issue number | 45 |
| Early online date | 14 Sep 2012 |
| DOIs | |
| Publication status | Published - 7 Dec 2012 |
| Externally published | Yes |
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Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. / Lucas, Stephanie J.; Lord, Rianne M.; Wilson, Rachel L.; Phillips, Roger M.; Sridharan, Visuvanathar; McGowan, Patrick C.
In: Dalton Transactions, Vol. 41, No. 45, 07.12.2012, p. 13800-13802.Research output: Contribution to journal › Article
TY - JOUR
T1 - Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents
AU - Lucas, Stephanie J.
AU - Lord, Rianne M.
AU - Wilson, Rachel L.
AU - Phillips, Roger M.
AU - Sridharan, Visuvanathar
AU - McGowan, Patrick C.
PY - 2012/12/7
Y1 - 2012/12/7
N2 - Several Ru-arene and Ir-Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.
AB - Several Ru-arene and Ir-Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.
UR - http://www.scopus.com/inward/record.url?scp=84868117273&partnerID=8YFLogxK
UR - http://pubs.rsc.org/en/journals/journal/dt
U2 - 10.1039/c2dt32104a
DO - 10.1039/c2dt32104a
M3 - Article
VL - 41
SP - 13800
EP - 13802
JO - Dalton Transactions
JF - Dalton Transactions
SN - 1477-9226
IS - 45
ER -