Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

Stephanie J. Lucas, Rianne M. Lord, Rachel L. Wilson, Roger M. Phillips, Visuvanathar Sridharan, Patrick C. McGowan

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Several Ru-arene and Ir-Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.

Original languageEnglish
Pages (from-to)13800-13802
Number of pages3
JournalDalton Transactions
Volume41
Issue number45
Early online date14 Sep 2012
DOIs
Publication statusPublished - 7 Dec 2012
Externally publishedYes

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Iridium
Ruthenium
Ligands
Coordination Complexes
Cells

Cite this

Lucas, Stephanie J. ; Lord, Rianne M. ; Wilson, Rachel L. ; Phillips, Roger M. ; Sridharan, Visuvanathar ; McGowan, Patrick C. / Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. In: Dalton Transactions. 2012 ; Vol. 41, No. 45. pp. 13800-13802.
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Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. / Lucas, Stephanie J.; Lord, Rianne M.; Wilson, Rachel L.; Phillips, Roger M.; Sridharan, Visuvanathar; McGowan, Patrick C.

In: Dalton Transactions, Vol. 41, No. 45, 07.12.2012, p. 13800-13802.

Research output: Contribution to journalArticle

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