Abstract
Cyrene as a bio-alternative solvent: a highly efficient, waste minimizing protocol for the synthesis of ureas from isocyanates and secondary amines in the bio-available solvent Cyrene is reported. This method eliminated the use of toxic solvents, such as DMF, and established a simple work-up procedure for removal of the Cyrene, which led to a 28-fold increase in molar efficiency versus industrial standard protocols.
Original language | English |
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Pages (from-to) | 2123-2128 |
Number of pages | 6 |
Journal | Green Chemistry |
Volume | 19 |
Issue number | 9 |
Early online date | 24 Apr 2017 |
DOIs | |
Publication status | Published - 7 May 2017 |