Through careful choice of conditions, 2-(N-indolyl) amides can be directed to undergo selectively either enolate arylation to give oxindoles or direct arylation to give indolo-fused benzodiazepines. The former chemistry facilitates the synthesis of the hexahydropyrrolindole core of psychotrimine.
|Number of pages||5|
|Early online date||9 Nov 2015|
|Publication status||Published - 4 Jan 2016|