Synthetic Studies on Psychotrimine: Palladium-Catalysed Arylation of 2-(N -Indolyl) Amides

Emma L. Watson, Anthony Ball, Steven A. Raw, Stephen P. Marsden

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Through careful choice of conditions, 2-(N-indolyl) amides can be directed to undergo selectively either enolate arylation to give oxindoles or direct arylation to give indolo-fused benzodiazepines. The former chemistry facilitates the synthesis of the hexahydropyrrolindole core of psychotrimine.
Original languageEnglish
Pages (from-to)146-150
Number of pages5
JournalSynlett
Volume27
Issue number1
Early online date9 Nov 2015
DOIs
Publication statusPublished - 4 Jan 2016
Externally publishedYes

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