Telephone-supported computerised cognitive–behavioural therapy: REEACT-2 large-scale pragmatic randomised controlled trial

Simon Gilbody, Sally Brabyn, Karina Lovell, David Kessler, Thomas Devlin, Lucy Smith, Ricardo Araya, Michael Barkham, Peter Bower, Cindy Cooper, Sarah Knowles, Elizabeth Littlewood, David A. Richards, Debbie Tallon, David Whire, Gillian Worthy

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62 Citations (Scopus)

Abstract

Background
Computerised cognitive–behavioural therapy (cCBT) for depression has the potential to be efficient therapy but engagement is poor in primary care trials.

Aims
We tested the benefits of adding telephone support to cCBT.

Method
We compared telephone-facilitated cCBT (MoodGYM) (n = 187) to minimally supported cCBT (MoodGYM) (n = 182) in a pragmatic randomised trial (trial registration: ISRCTN55310481). Outcomes were depression severity (Patient Health Questionnaire (PHQ)-9), anxiety (Generalized Anxiety Disorder Questionnaire (GAD)-7) and somatoform complaints (PHQ-15) at 4 and 12 months.

Results
Use of cCBT increased by a factor of between 1.5 and 2 with telephone facilitation. At 4 months PHQ-9 scores were 1.9 points lower (95% CI 0.5–3.3) for telephone-supported cCBT. At 12 months, the results were no longer statistically significant (0.9 PHQ-9 points, 95% CI −0.5 to 2.3). There was improvement in anxiety scores and for somatic complaints.

Conclusions
Telephone facilitation of cCBT improves engagement and expedites depression improvement. The effect was small to moderate and comparable with other low-intensity psychological interventions.
Original languageEnglish
Pages (from-to)362-367
Number of pages6
JournalBritish Journal of Psychiatry
Volume210
Issue number5
DOIs
Publication statusPublished - 1 May 2017
Externally publishedYes

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