The anti-diabetic potential of polysaccharides extracted from members of the cucurbit family: A review

Rachel Simpson, Gordon A. Morris

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Diabetes is a growing global problem and a heavy financial burden on health care services. It is estimated that over 380 million people suffer from this condition which causes many deaths each year in addition to being associated with increased risk of other health problems. Traditional medicine is a promising area of research in diabetes therapy as it is widely accessible and it is believed that over 200 plants have anti-diabetic properties including members of the cucurbit family. Studies in animal and human models have shown that treatment with some cucurbits has hypoglycaemic effects and stimulates beta cell regeneration in addition to other anti-diabetic effects which are equal to that of commonly prescribed anti-diabetic drugs. It has also been shown that at least one of the bioactive components which stimulate these effects is a polysaccharide.
Original languageEnglish
Pages (from-to)106-114
Number of pages9
JournalBioactive Carbohydrates and Dietary Fibre
Volume3
Issue number2
DOIs
Publication statusPublished - Apr 2014

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glycemic effect
Cucurbitaceae
Medical problems
Polysaccharides
diabetes
polysaccharides
hypoglycemic agents
Traditional Medicine
traditional medicine
Hypoglycemic Agents
health services
Health Services
Regeneration
Cause of Death
Animal Models
death
Delivery of Health Care
Health care
therapeutics
Medicine

Cite this

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abstract = "Diabetes is a growing global problem and a heavy financial burden on health care services. It is estimated that over 380 million people suffer from this condition which causes many deaths each year in addition to being associated with increased risk of other health problems. Traditional medicine is a promising area of research in diabetes therapy as it is widely accessible and it is believed that over 200 plants have anti-diabetic properties including members of the cucurbit family. Studies in animal and human models have shown that treatment with some cucurbits has hypoglycaemic effects and stimulates beta cell regeneration in addition to other anti-diabetic effects which are equal to that of commonly prescribed anti-diabetic drugs. It has also been shown that at least one of the bioactive components which stimulate these effects is a polysaccharide.",
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The anti-diabetic potential of polysaccharides extracted from members of the cucurbit family: A review. / Simpson, Rachel; Morris, Gordon A.

In: Bioactive Carbohydrates and Dietary Fibre, Vol. 3, No. 2, 04.2014, p. 106-114.

Research output: Contribution to journalArticle

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