The application of phenotypic microarray analysis to anti-fungal drug development

Darren Greetham, David F. Lappin, Ranjith Rajendran, Lindsay O'Donnell, Leighann Sherry, Gordon Ramage, Christopher Nile

Research output: Contribution to journalArticle

2 Citations (Scopus)


Candida albicans metabolic activity in the presence and absence of acetylcholine was measured using phenotypic microarray analysis. Acetylcholine inhibited C. albicans biofilm formation by slowing metabolism independent of biofilm forming capabilities. Phenotypic microarray analysis can therefore be used for screening compound libraries for novel anti-fungal drugs and measuring antifungal resistance.

Original languageEnglish
Pages (from-to)35-37
Number of pages3
JournalJournal of Microbiological Methods
Early online date9 Jan 2017
Publication statusPublished - 1 Mar 2017
Externally publishedYes


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