The directed lithiation of some 3-acylchromone acetals

G. Elena Daia, Christopher D. Gabbutt, John D. Hepworth, B. Mark Heron, David E. Hibbs, Michael B. Hursthouse

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


3-Acylchromone acetals are lithiated at C-2. Subsequent electrophilic trapping gives chromones 4 together with a ring-contracted dimer 6. During the formation of some acetals, an acid-catalysed rearrangement to a 2-substituted 3-formylchromone acetal is observed.

Original languageEnglish
Pages (from-to)1215-1218
Number of pages4
JournalTetrahedron Letters
Issue number10
Publication statusPublished - 5 Mar 1998
Externally publishedYes


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