The mitochondrial DNA tree and forensic science

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Studies of mitochondrial DNA (mtDNA) began with simple restriction assays, moved on to high-resolution restriction analysis and control-region sequencing, and now make use of complete mtDNA sequences. Forensic labs have, by and large, continued to rely on the use of control-region databases, but these databases often contain a disconcertingly large number of sequence errors. A phylogenetic approach to mtDNA data sets can help to uncover such errors, and it is argued that an understanding of both the phylogenetic and phylogeographic context of mtDNA lineages is a valuable tool from which the forensics community can benefit.

Original languageEnglish
Pages (from-to)91-93
Number of pages3
JournalInternational Congress Series
Volume1261
Issue numberC
DOIs
Publication statusPublished - Apr 2004

Fingerprint

Forensic Sciences
Mitochondrial DNA
Databases

Cite this

@article{e81beb2431ca4133b5cf180af4ff93e8,
title = "The mitochondrial DNA tree and forensic science",
abstract = "Studies of mitochondrial DNA (mtDNA) began with simple restriction assays, moved on to high-resolution restriction analysis and control-region sequencing, and now make use of complete mtDNA sequences. Forensic labs have, by and large, continued to rely on the use of control-region databases, but these databases often contain a disconcertingly large number of sequence errors. A phylogenetic approach to mtDNA data sets can help to uncover such errors, and it is argued that an understanding of both the phylogenetic and phylogeographic context of mtDNA lineages is a valuable tool from which the forensics community can benefit.",
keywords = "Genealogy, Mitochondrial DNA (mtDNA), Phylogenetic, Phylogeography",
author = "Martin Richards",
year = "2004",
month = "4",
doi = "10.1016/S0531-5131(03)01704-7",
language = "English",
volume = "1261",
pages = "91--93",
journal = "International Congress Series",
issn = "0531-5131",
publisher = "Elsevier",
number = "C",

}

The mitochondrial DNA tree and forensic science. / Richards, Martin.

In: International Congress Series, Vol. 1261, No. C, 04.2004, p. 91-93.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The mitochondrial DNA tree and forensic science

AU - Richards, Martin

PY - 2004/4

Y1 - 2004/4

N2 - Studies of mitochondrial DNA (mtDNA) began with simple restriction assays, moved on to high-resolution restriction analysis and control-region sequencing, and now make use of complete mtDNA sequences. Forensic labs have, by and large, continued to rely on the use of control-region databases, but these databases often contain a disconcertingly large number of sequence errors. A phylogenetic approach to mtDNA data sets can help to uncover such errors, and it is argued that an understanding of both the phylogenetic and phylogeographic context of mtDNA lineages is a valuable tool from which the forensics community can benefit.

AB - Studies of mitochondrial DNA (mtDNA) began with simple restriction assays, moved on to high-resolution restriction analysis and control-region sequencing, and now make use of complete mtDNA sequences. Forensic labs have, by and large, continued to rely on the use of control-region databases, but these databases often contain a disconcertingly large number of sequence errors. A phylogenetic approach to mtDNA data sets can help to uncover such errors, and it is argued that an understanding of both the phylogenetic and phylogeographic context of mtDNA lineages is a valuable tool from which the forensics community can benefit.

KW - Genealogy

KW - Mitochondrial DNA (mtDNA)

KW - Phylogenetic

KW - Phylogeography

UR - http://www.scopus.com/inward/record.url?scp=59349119397&partnerID=8YFLogxK

U2 - 10.1016/S0531-5131(03)01704-7

DO - 10.1016/S0531-5131(03)01704-7

M3 - Article

VL - 1261

SP - 91

EP - 93

JO - International Congress Series

JF - International Congress Series

SN - 0531-5131

IS - C

ER -