The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task

Robin Paul Wilson, Marco Colizzi, Matthijs Geert Bossong, Paul Allen, Matthew Kempton, MTAC, A. Murphy, Sagnik Bhattacharyya

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.

Original languageEnglish
Pages (from-to)496-506
Number of pages11
JournalNeuropsychology Review
Volume28
Issue number4
DOIs
Publication statusPublished - 25 Sep 2018
Externally publishedYes

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Reward
Meta-Analysis
Motivation
Magnetic Resonance Imaging
Health
Brain
Gyrus Cinguli
Prefrontal Cortex

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Wilson, Robin Paul ; Colizzi, Marco ; Bossong, Matthijs Geert ; Allen, Paul ; Kempton, Matthew ; MTAC ; Murphy, A. ; Bhattacharyya, Sagnik. / The Neural Substrate of Reward Anticipation in Health : A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task. In: Neuropsychology Review. 2018 ; Vol. 28, No. 4. pp. 496-506.
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The Neural Substrate of Reward Anticipation in Health : A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task. / Wilson, Robin Paul; Colizzi, Marco; Bossong, Matthijs Geert; Allen, Paul; Kempton, Matthew; MTAC ; Murphy, A.; Bhattacharyya, Sagnik.

In: Neuropsychology Review, Vol. 28, No. 4, 25.09.2018, p. 496-506.

Research output: Contribution to journalArticle

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