The Origins of the Polynesians:

An Interpretation from Mitochondrial Lineage Analysis

B. Sykes, A. Leiboff, J. Low-Beer, S. Tetzner, M. Richards

Research output: Contribution to journalArticle

160 Citations (Scopus)

Abstract

Using mitochondrial lineage analysis of 1,178 individuals from Polynesia, the western Pacific, and Taiwan, we show that the major prehistoric settlement of Polynesia was from the west and involved two or possibly three genetically distinct populations. The predominant lineage group, accounting for 94% of Polynesian mtDNA, shares a 9-bp COII/tRNA(Lys) intergenic deletion and characteristic control region transition variants, compared to the Cambridge reference sequence. In Polynesia, the diversity of this group is extremely restricted, while related lineages in Indonesia, the Philippines, and Taiwan are increasingly diverse. This suggests a relatively recent major eastward expansion into Polynesia, perhaps originating from Taiwan, in agreement with archaeological and linguistic evidence, but which experienced one or more severe population bottlenecks. The second mitochondrial lineage group, accounting for 3.5% of Polynesian mtDNA haplotypes, does not have the 9-bp deletion and is characterized by an A-C transversional variant at nt position 16265. Specific oligonucleotides for this variant were used to select individuals from the population sample who, with other sequences, show that the Polynesian lineages were part of a diverse group in Vanuatu and Papua New Guinea. The very low overall diversity of both lineage groups in Polynesia suggests there was severe population restriction during the colonization of remote Oceania. A third group, represented by only four individuals (0.6%) in Polynesia but also present in the Philippines, shares variants at nt positions 16172 and 16304. Two Polynesians had unrelated haplotypes matching published sequences from native South Americans, which may be the first genetic evidence of prehistoric human contact between Polynesia and South America.

Original languageEnglish
Pages (from-to)1463-1475
Number of pages13
JournalAmerican Journal of Human Genetics
Volume57
Issue number6
Publication statusPublished - Dec 1995
Externally publishedYes

Fingerprint

Polynesia
Taiwan
Philippines
Mitochondrial DNA
Haplotypes
Population
Vanuatu
RNA, Transfer, Lys
Oceania
Papua New Guinea
Indonesia
North American Indians
South America
Linguistics
Oligonucleotides

Cite this

Sykes, B. ; Leiboff, A. ; Low-Beer, J. ; Tetzner, S. ; Richards, M. / The Origins of the Polynesians: An Interpretation from Mitochondrial Lineage Analysis. In: American Journal of Human Genetics. 1995 ; Vol. 57, No. 6. pp. 1463-1475.
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The Origins of the Polynesians: An Interpretation from Mitochondrial Lineage Analysis. / Sykes, B.; Leiboff, A.; Low-Beer, J.; Tetzner, S.; Richards, M.

In: American Journal of Human Genetics, Vol. 57, No. 6, 12.1995, p. 1463-1475.

Research output: Contribution to journalArticle

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