The resolution of racemic 1,2-diols by the esterase catalysed hydrolysis of the corresponding cyclic carbonate

Patrick Barton, Michael I. Page

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Racemic 1-phenyl-1,2-ethane diol can be resolved by the pig liver esterase catalysed hydrolysis of the corresponding cyclic carbonate to give the (R) and (S) 1-phenyl-1,2-ethane diol with an ee of 97 and 78% respectively.

Original languageEnglish
Pages (from-to)7731-7734
Number of pages4
JournalTetrahedron
Volume48
Issue number36
DOIs
Publication statusPublished - 4 Sep 1992

    Fingerprint

Cite this