The TB structural genomics consortium: Providing a structural foundation for drug discovery

The TB Structural Genomics Consortium, Kirsty J. McLean

Research output: Contribution to journalReview articlepeer-review

76 Citations (Scopus)

Abstract

Structural genomics, the large-scale determination of protein structures, promises to provide a broad structural foundation for drug discovery. The tuberculosis (TB) Structural Genomics Consortium is devoted to encouraging, coordinating, and facilitating the determination of structures of proteins from Mycobacterium tuberculosis and hopes to determine 400 TB protein structures over 5 years. The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts.

Original languageEnglish
Pages (from-to)121-141
Number of pages21
JournalCurrent Drug Targets - Infectious Disorders
Volume2
Issue number2
DOIs
Publication statusPublished - 2002
Externally publishedYes

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