The Twisted Amide 2-Quinuclidone: 60 Years in the Making

Jonathan Clayden; Wesley J. Moran

doi:10.1002/anie.200603016

The Twisted Amide 2-Quinuclidone: 60 Years in the Making

Jonathan Clayden, Wesley J. Moran

Research output: Contribution to journal › Short survey › peer-review

68 Citations (Scopus)

Abstract

No longer left to the imagination: Non-planar amides have intrigued chemists for decades. This year, a story 60 years in the making came to an end: 2-quinuclidone has finally been synthesized and isolated in the form of its HBF₄ salt (see scheme).

Original language	English
Pages (from-to)	7118-7120
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	43
Early online date	29 Sep 2006
DOIs	https://doi.org/10.1002/anie.200603016
Publication status	Published - 6 Nov 2006
Externally published	Yes

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title = "The Twisted Amide 2-Quinuclidone: 60 Years in the Making",

abstract = "No longer left to the imagination: Non-planar amides have intrigued chemists for decades. This year, a story 60 years in the making came to an end: 2-quinuclidone has finally been synthesized and isolated in the form of its HBF4 salt (see scheme).",

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AU - Moran, Wesley J.

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KW - Amides

KW - Penicillin

KW - Reactivity

KW - Strained molecules

KW - Synthetic methods

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DO - 10.1002/anie.200603016

M3 - Short survey

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The Twisted Amide 2-Quinuclidone: 60 Years in the Making

Abstract

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