The Twisted Amide 2-Quinuclidone

60 Years in the Making

Jonathan Clayden, Wesley J. Moran

Research output: Contribution to journalShort survey

59 Citations (Scopus)

Abstract

No longer left to the imagination: Non-planar amides have intrigued chemists for decades. This year, a story 60 years in the making came to an end: 2-quinuclidone has finally been synthesized and isolated in the form of its HBF4 salt (see scheme).

Original languageEnglish
Pages (from-to)7118-7120
Number of pages3
JournalAngewandte Chemie - International Edition
Volume45
Issue number43
Early online date29 Sep 2006
DOIs
Publication statusPublished - 6 Nov 2006
Externally publishedYes

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Amides
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2-quinuclidone

Cite this

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The Twisted Amide 2-Quinuclidone : 60 Years in the Making. / Clayden, Jonathan; Moran, Wesley J.

In: Angewandte Chemie - International Edition, Vol. 45, No. 43, 06.11.2006, p. 7118-7120.

Research output: Contribution to journalShort survey

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KW - Penicillin

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KW - Strained molecules

KW - Synthetic methods

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