Thermally mediated droplet formation in microchannels

Nam Trung Nguyen; Teck Hui Ting; Yit Fatt Yap; Teck Neng Wong; John Chee Kiong Chai; Wee Liat Ong; Junlong Zhou; Say Hwa Tan; Levent Yobas

doi:10.1063/1.2773948

Thermally mediated droplet formation in microchannels

Nam Trung Nguyen, Teck Hui Ting, Yit Fatt Yap, Teck Neng Wong, John Chee Kiong Chai, Wee Liat Ong, Junlong Zhou, Say Hwa Tan, Levent Yobas

Research output: Contribution to journal › Article › peer-review

108 Citations (Scopus)

Abstract

Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the droplet formation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 °C, the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples.

Original language	English
Article number	084102
Journal	Applied Physics Letters
Volume	91
Issue number	8
DOIs	https://doi.org/10.1063/1.2773948
Publication status	Published - 20 Aug 2007
Externally published	Yes

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title = "Thermally mediated droplet formation in microchannels",

abstract = "Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the droplet formation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 °C, the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples.",

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AU - Nguyen, Nam Trung

AU - Ting, Teck Hui

AU - Yap, Yit Fatt

AU - Wong, Teck Neng

AU - Chai, John Chee Kiong

AU - Ong, Wee Liat

AU - Zhou, Junlong

AU - Tan, Say Hwa

AU - Yobas, Levent

PY - 2007/8/20

Y1 - 2007/8/20

N2 - Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the droplet formation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 °C, the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples.

AB - Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The droplet formation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the droplet formation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 °C, the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples.

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ER -

Thermally mediated droplet formation in microchannels

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