This letter details the formation of 18-membered macrocyclic spirocyclic esters and ethers from readily prepared tetraene precursors via tandem metathesis reactions. Factors which control the course of these transition metal catalysed processes are discussed and the crystal structures of the novel macrocycles obtained are delineated.
|Number of pages||4|
|Early online date||3 Oct 2002|
|Publication status||Published - 28 Oct 2002|