Use of corticosteroids in asthma and COPD patients with or without COVID-19

Syed Shahzad Hasan; Toby  Capstick; Syed Tabish Razi Zaidi; Chia Siang Kow; Hamid Merchant

doi:10.1016/j.rmed.2020.106045

Use of corticosteroids in asthma and COPD patients with or without COVID-19

Syed Shahzad Hasan, Toby Capstick, Syed Tabish Razi Zaidi, Chia Siang Kow, Hamid Merchant

Research output: Contribution to journal › Review article › peer-review

33 Citations (Scopus)

Abstract

The potential detrimental effects of steroids on the immune system to fight viral infections had always been a concern for patients on long term steroids in chronic conditions. A recent warning from WHO on systemic corticosteroid use amid COVID-19 raised suspicion among public and healthcare professionals regarding the safety of steroid use during the SARS-CoV-2 pandemic. The corticosteroids (inhaled and oral) are commonly prescribed in the management of asthma and COPD patients and any unsolicited changes in medications use may lead to potentially severe exacerbations and may risk patient lives. This article provides a critical review of clinical evidence and offers a detailed discussion on the safety and efficacy of corticosteroids in asthma and COPD patients, both with and without COVID-19.

Original language	English
Article number	106045
Number of pages	5
Journal	Respiratory Medicine
Volume	170
Early online date	26 May 2020
DOIs	https://doi.org/10.1016/j.rmed.2020.106045
Publication status	Published - 1 Aug 2020

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10.1016/j.rmed.2020.106045Licence: Unspecified

Cite this

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title = "Use of corticosteroids in asthma and COPD patients with or without COVID-19",

abstract = "The potential detrimental effects of steroids on the immune system to fight viral infections had always been a concern for patients on long term steroids in chronic conditions. A recent warning from WHO on systemic corticosteroid use amid COVID-19 raised suspicion among public and healthcare professionals regarding the safety of steroid use during the SARS-CoV-2 pandemic. The corticosteroids (inhaled and oral) are commonly prescribed in the management of asthma and COPD patients and any unsolicited changes in medications use may lead to potentially severe exacerbations and may risk patient lives. This article provides a critical review of clinical evidence and offers a detailed discussion on the safety and efficacy of corticosteroids in asthma and COPD patients, both with and without COVID-19.",

keywords = "Asthma, Chronic obstructive pulmonary disease, Coronavirus disease 2019, Inhaled corticosteroid, Oral corticosteroid",

author = "Hasan, {Syed Shahzad} and Toby Capstick and {Razi Zaidi}, {Syed Tabish} and Kow, {Chia Siang} and Hamid Merchant",

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doi = "10.1016/j.rmed.2020.106045",

language = "English",

volume = "170",

journal = "Respiratory Medicine",

issn = "0954-6111",

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TY - JOUR

T1 - Use of corticosteroids in asthma and COPD patients with or without COVID-19

AU - Hasan, Syed Shahzad

AU - Capstick, Toby

AU - Razi Zaidi, Syed Tabish

AU - Kow, Chia Siang

AU - Merchant, Hamid

PY - 2020/8/1

Y1 - 2020/8/1

N2 - The potential detrimental effects of steroids on the immune system to fight viral infections had always been a concern for patients on long term steroids in chronic conditions. A recent warning from WHO on systemic corticosteroid use amid COVID-19 raised suspicion among public and healthcare professionals regarding the safety of steroid use during the SARS-CoV-2 pandemic. The corticosteroids (inhaled and oral) are commonly prescribed in the management of asthma and COPD patients and any unsolicited changes in medications use may lead to potentially severe exacerbations and may risk patient lives. This article provides a critical review of clinical evidence and offers a detailed discussion on the safety and efficacy of corticosteroids in asthma and COPD patients, both with and without COVID-19.

AB - The potential detrimental effects of steroids on the immune system to fight viral infections had always been a concern for patients on long term steroids in chronic conditions. A recent warning from WHO on systemic corticosteroid use amid COVID-19 raised suspicion among public and healthcare professionals regarding the safety of steroid use during the SARS-CoV-2 pandemic. The corticosteroids (inhaled and oral) are commonly prescribed in the management of asthma and COPD patients and any unsolicited changes in medications use may lead to potentially severe exacerbations and may risk patient lives. This article provides a critical review of clinical evidence and offers a detailed discussion on the safety and efficacy of corticosteroids in asthma and COPD patients, both with and without COVID-19.

KW - Asthma

KW - Chronic obstructive pulmonary disease

KW - Coronavirus disease 2019

KW - Inhaled corticosteroid

KW - Oral corticosteroid

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U2 - 10.1016/j.rmed.2020.106045

DO - 10.1016/j.rmed.2020.106045

M3 - Review article

VL - 170

JO - Respiratory Medicine

JF - Respiratory Medicine

SN - 0954-6111

M1 - 106045

ER -

Use of corticosteroids in asthma and COPD patients with or without COVID-19

Abstract

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Cite this

Use of corticosteroids in asthma and COPD patients with or without COVID-19

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Research output

Why COVID vaccines for young children (5–11 years) are not essential at this moment in time?

Lactoferrin reduces the risk of respiratory tract infections: A meta-analysis of randomized controlled trials

Dexamethasone and CoViD-19: RECOVERY trial provided invaluable clinical evidence but costed precious lives!

Press/Media

Lactoferrin supplements could aid recovery of COVID19 and other Respiratory Infections

CoViD Now: Debunking Myths of the Virus

Huddersfield research predicted anti-COVID steroid benefits

Study says inhalers OK to use amid COVID-19 concerns

Cite this