Validity and reliability of the St. George's respiratory questionnaire in assessing health status in patients with chronic pulmonary aspergillosis

Khaled Al-Shair, Graham T.W. Atherton, Deborah Kennedy, Georgina Powell, David W. Denning, Ann Caress

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background: Chronic pulmonary aspergillosis (CPA) markedly reduces lung function through progressive lung destruction. To date, however, health status in patients with CPA has not been studied. This is due, in part, to a lack of adequately validated scales. The St. George's Respiratory Questionnaire (SGRQ) is widely used for several chronic respiratory diseases, but not for CPA. We examined the reliability and validity of SGRQ in CPA. Methods: Eighty-eight patients with CPA completed the SGRQ, the Short Form-36 Health Survey (SF-36), and the Medical Research Council (MRC) dyspnea scale. Lung function and BMI were also measured. Pearson correlation, t test, analysis of variance, and their equivalents for nonparametric data and multivariate linear and binary analyses were used. Results: The SGRQ components (symptoms, activity, and impact) and total scores achieved high internal consistency (Cronbach α = 0.77, 0.91, 0.86, and 0.94), and SGRQ components had good intercorrelation (r ≥ 0.41; P < .001) and correlated well with the total score (r ≥ 0.63; P < .001). There were high, intraclass, correlation coeffi cients for the total SGRQ and its dimensions (≥ 0.92). The SGRQ scores showed signifi cant correlation with the MRC dyspnea scale and SF-36 components and differentiated between all grades of shortness of breath and different bands of disease severity (P < .05). In addition, patients with greater clinician-rated disease severity had more impairment of health status (P < .006). CPA severity was independently associated with impairment in health status, and COPD comorbidity signifi cantly affected the health status in patients with CPA. Conclusions: SGRQ demonstrated a signifi cant level of reliability and validity in measuring health status in CPA.

LanguageEnglish
Pages623-631
Number of pages9
JournalChest
Volume144
Issue number2
DOIs
Publication statusPublished - 1 Aug 2013
Externally publishedYes

Fingerprint

Pulmonary Aspergillosis
Reproducibility of Results
Health Status
Dyspnea
Lung
Biomedical Research
Surveys and Questionnaires
Health Surveys
Chronic Obstructive Pulmonary Disease
Comorbidity
Analysis of Variance
Chronic Disease

Cite this

Al-Shair, Khaled ; Atherton, Graham T.W. ; Kennedy, Deborah ; Powell, Georgina ; Denning, David W. ; Caress, Ann. / Validity and reliability of the St. George's respiratory questionnaire in assessing health status in patients with chronic pulmonary aspergillosis. In: Chest. 2013 ; Vol. 144, No. 2. pp. 623-631.
@article{f48100abb56943d9b07094b4afc41816,
title = "Validity and reliability of the St. George's respiratory questionnaire in assessing health status in patients with chronic pulmonary aspergillosis",
abstract = "Background: Chronic pulmonary aspergillosis (CPA) markedly reduces lung function through progressive lung destruction. To date, however, health status in patients with CPA has not been studied. This is due, in part, to a lack of adequately validated scales. The St. George's Respiratory Questionnaire (SGRQ) is widely used for several chronic respiratory diseases, but not for CPA. We examined the reliability and validity of SGRQ in CPA. Methods: Eighty-eight patients with CPA completed the SGRQ, the Short Form-36 Health Survey (SF-36), and the Medical Research Council (MRC) dyspnea scale. Lung function and BMI were also measured. Pearson correlation, t test, analysis of variance, and their equivalents for nonparametric data and multivariate linear and binary analyses were used. Results: The SGRQ components (symptoms, activity, and impact) and total scores achieved high internal consistency (Cronbach α = 0.77, 0.91, 0.86, and 0.94), and SGRQ components had good intercorrelation (r ≥ 0.41; P < .001) and correlated well with the total score (r ≥ 0.63; P < .001). There were high, intraclass, correlation coeffi cients for the total SGRQ and its dimensions (≥ 0.92). The SGRQ scores showed signifi cant correlation with the MRC dyspnea scale and SF-36 components and differentiated between all grades of shortness of breath and different bands of disease severity (P < .05). In addition, patients with greater clinician-rated disease severity had more impairment of health status (P < .006). CPA severity was independently associated with impairment in health status, and COPD comorbidity signifi cantly affected the health status in patients with CPA. Conclusions: SGRQ demonstrated a signifi cant level of reliability and validity in measuring health status in CPA.",
author = "Khaled Al-Shair and Atherton, {Graham T.W.} and Deborah Kennedy and Georgina Powell and Denning, {David W.} and Ann Caress",
year = "2013",
month = "8",
day = "1",
doi = "10.1378/chest.12-0014",
language = "English",
volume = "144",
pages = "623--631",
journal = "Chest",
issn = "0012-3692",
publisher = "American College of Chest Physicians",
number = "2",

}

Validity and reliability of the St. George's respiratory questionnaire in assessing health status in patients with chronic pulmonary aspergillosis. / Al-Shair, Khaled; Atherton, Graham T.W.; Kennedy, Deborah; Powell, Georgina; Denning, David W.; Caress, Ann.

In: Chest, Vol. 144, No. 2, 01.08.2013, p. 623-631.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Validity and reliability of the St. George's respiratory questionnaire in assessing health status in patients with chronic pulmonary aspergillosis

AU - Al-Shair, Khaled

AU - Atherton, Graham T.W.

AU - Kennedy, Deborah

AU - Powell, Georgina

AU - Denning, David W.

AU - Caress, Ann

PY - 2013/8/1

Y1 - 2013/8/1

N2 - Background: Chronic pulmonary aspergillosis (CPA) markedly reduces lung function through progressive lung destruction. To date, however, health status in patients with CPA has not been studied. This is due, in part, to a lack of adequately validated scales. The St. George's Respiratory Questionnaire (SGRQ) is widely used for several chronic respiratory diseases, but not for CPA. We examined the reliability and validity of SGRQ in CPA. Methods: Eighty-eight patients with CPA completed the SGRQ, the Short Form-36 Health Survey (SF-36), and the Medical Research Council (MRC) dyspnea scale. Lung function and BMI were also measured. Pearson correlation, t test, analysis of variance, and their equivalents for nonparametric data and multivariate linear and binary analyses were used. Results: The SGRQ components (symptoms, activity, and impact) and total scores achieved high internal consistency (Cronbach α = 0.77, 0.91, 0.86, and 0.94), and SGRQ components had good intercorrelation (r ≥ 0.41; P < .001) and correlated well with the total score (r ≥ 0.63; P < .001). There were high, intraclass, correlation coeffi cients for the total SGRQ and its dimensions (≥ 0.92). The SGRQ scores showed signifi cant correlation with the MRC dyspnea scale and SF-36 components and differentiated between all grades of shortness of breath and different bands of disease severity (P < .05). In addition, patients with greater clinician-rated disease severity had more impairment of health status (P < .006). CPA severity was independently associated with impairment in health status, and COPD comorbidity signifi cantly affected the health status in patients with CPA. Conclusions: SGRQ demonstrated a signifi cant level of reliability and validity in measuring health status in CPA.

AB - Background: Chronic pulmonary aspergillosis (CPA) markedly reduces lung function through progressive lung destruction. To date, however, health status in patients with CPA has not been studied. This is due, in part, to a lack of adequately validated scales. The St. George's Respiratory Questionnaire (SGRQ) is widely used for several chronic respiratory diseases, but not for CPA. We examined the reliability and validity of SGRQ in CPA. Methods: Eighty-eight patients with CPA completed the SGRQ, the Short Form-36 Health Survey (SF-36), and the Medical Research Council (MRC) dyspnea scale. Lung function and BMI were also measured. Pearson correlation, t test, analysis of variance, and their equivalents for nonparametric data and multivariate linear and binary analyses were used. Results: The SGRQ components (symptoms, activity, and impact) and total scores achieved high internal consistency (Cronbach α = 0.77, 0.91, 0.86, and 0.94), and SGRQ components had good intercorrelation (r ≥ 0.41; P < .001) and correlated well with the total score (r ≥ 0.63; P < .001). There were high, intraclass, correlation coeffi cients for the total SGRQ and its dimensions (≥ 0.92). The SGRQ scores showed signifi cant correlation with the MRC dyspnea scale and SF-36 components and differentiated between all grades of shortness of breath and different bands of disease severity (P < .05). In addition, patients with greater clinician-rated disease severity had more impairment of health status (P < .006). CPA severity was independently associated with impairment in health status, and COPD comorbidity signifi cantly affected the health status in patients with CPA. Conclusions: SGRQ demonstrated a signifi cant level of reliability and validity in measuring health status in CPA.

UR - http://www.scopus.com/inward/record.url?scp=84881489394&partnerID=8YFLogxK

U2 - 10.1378/chest.12-0014

DO - 10.1378/chest.12-0014

M3 - Article

VL - 144

SP - 623

EP - 631

JO - Chest

T2 - Chest

JF - Chest

SN - 0012-3692

IS - 2

ER -