Variations on a (t)heme - Novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

Andrew W. Munro; Hazel M. Girvan; Kirsty J. McLean

doi:10.1039/b604190f

Variations on a (t)heme - Novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

Andrew W. Munro, Hazel M. Girvan, Kirsty J. McLean

Research output: Contribution to journal › Review article › peer-review

234 Citations (Scopus)

Abstract

The catalytic potential of the P450s in organic biotransformations is the subject of this review - with emphasis on the breadth of P450 redox systems now recognised and the catalytic versatility of these biotechnologically important enzymes.

Original language	English
Pages (from-to)	585-609
Number of pages	25
Journal	Natural Product Reports
Volume	24
Issue number	3
DOIs	https://doi.org/10.1039/b604190f
Publication status	Published - 4 May 2007
Externally published	Yes

Access to Document

10.1039/b604190fLicence: Unspecified

Cite this

@article{ea73e0cacacd43b4b470d907f725bda8,

title = "Variations on a (t)heme - Novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily",

abstract = "The catalytic potential of the P450s in organic biotransformations is the subject of this review - with emphasis on the breadth of P450 redox systems now recognised and the catalytic versatility of these biotechnologically important enzymes.",

keywords = "Catalysis, Cytochrome P-450 Enzyme System, Heme, Oxidation-Reduction, Protein Conformation, Substrate Specificity",

author = "Munro, {Andrew W.} and Girvan, {Hazel M.} and McLean, {Kirsty J.}",

year = "2007",

month = may,

day = "4",

doi = "10.1039/b604190f",

language = "English",

volume = "24",

pages = "585--609",

journal = "Natural Product Reports",

issn = "0265-0568",

publisher = "Royal Society of Chemistry",

number = "3",

}

TY - JOUR

T1 - Variations on a (t)heme - Novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

AU - Munro, Andrew W.

AU - Girvan, Hazel M.

AU - McLean, Kirsty J.

PY - 2007/5/4

Y1 - 2007/5/4

N2 - The catalytic potential of the P450s in organic biotransformations is the subject of this review - with emphasis on the breadth of P450 redox systems now recognised and the catalytic versatility of these biotechnologically important enzymes.

AB - The catalytic potential of the P450s in organic biotransformations is the subject of this review - with emphasis on the breadth of P450 redox systems now recognised and the catalytic versatility of these biotechnologically important enzymes.

KW - Catalysis

KW - Cytochrome P-450 Enzyme System

KW - Heme

KW - Oxidation-Reduction

KW - Protein Conformation

KW - Substrate Specificity

UR - http://www.scopus.com/inward/record.url?scp=34249819058&partnerID=8YFLogxK

U2 - 10.1039/b604190f

DO - 10.1039/b604190f

M3 - Review article

C2 - 17534532

AN - SCOPUS:34249819058

VL - 24

SP - 585

EP - 609

JO - Natural Product Reports

JF - Natural Product Reports

SN - 0265-0568

IS - 3

ER -

Variations on a (t)heme - Novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

Abstract

Access to Document

Other files and links

Fingerprint

Cite this