Viscosity effects on optically generated electron and nuclear spin hyperpolarization

Matthew W. Dale; Daniel Cheney; Claudio Vallotto; Chris Wedge

doi:10.1039/D0CP04012F

Viscosity effects on optically generated electron and nuclear spin hyperpolarization

Matthew W. Dale, Daniel Cheney, Claudio Vallotto, Chris Wedge

Research output: Contribution to journal › Article › peer-review

Abstract

Spin hyperpolarization can dramatically increase signal intensities in magnetic resonance experiments, providing either improved bulk sensitivity or additional spectroscopic detail through selective enhancements. While typical hyperpolarization approaches have utilized microwave irradiation, one emerging route is the use of optically generated triplet states. We report an investigation into the effects of solution viscosity on radical–triplet pair interactions, propose a new standard for quantification of the hyperpolarization in EPR experiments, and demonstrate a significant increase in the optically generated ¹H NMR signal enhancement upon addition of glycerol to aqueous solutions.

Original language	English
Number of pages	10
Journal	Physical Chemistry Chemical Physics
Early online date	8 Dec 2020
DOIs	https://doi.org/10.1039/D0CP04012F
Publication status	E-pub ahead of print - 8 Dec 2020

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10.1039/D0CP04012FLicence: CC BY

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1 Invited talk

Exploiting Radical Triplet Pair Hyperpolarization for Sensitivity Enhancement in Solution-State NMR
Matthew W. Dale (Speaker), Daniel Cheney (Speaker) & Chris Wedge (Speaker)
8 Nov 2019
Activity: Talk or presentation types › Invited talk

Cite this

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title = "Viscosity effects on optically generated electron and nuclear spin hyperpolarization",

abstract = "Spin hyperpolarization can dramatically increase signal intensities in magnetic resonance experiments, providing either improved bulk sensitivity or additional spectroscopic detail through selective enhancements. While typical hyperpolarization approaches have utilized microwave irradiation, one emerging route is the use of optically generated triplet states. We report an investigation into the effects of solution viscosity on radical–triplet pair interactions, propose a new standard for quantification of the hyperpolarization in EPR experiments, and demonstrate a significant increase in the optically generated 1H NMR signal enhancement upon addition of glycerol to aqueous solutions.",

keywords = "Nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR)",

author = "Dale, {Matthew W.} and Daniel Cheney and Claudio Vallotto and Chris Wedge",

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language = "English",

journal = "Physical Chemistry Chemical Physics",

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T1 - Viscosity effects on optically generated electron and nuclear spin hyperpolarization

AU - Dale, Matthew W.

AU - Cheney, Daniel

AU - Vallotto, Claudio

AU - Wedge, Chris

PY - 2020/12/8

Y1 - 2020/12/8

N2 - Spin hyperpolarization can dramatically increase signal intensities in magnetic resonance experiments, providing either improved bulk sensitivity or additional spectroscopic detail through selective enhancements. While typical hyperpolarization approaches have utilized microwave irradiation, one emerging route is the use of optically generated triplet states. We report an investigation into the effects of solution viscosity on radical–triplet pair interactions, propose a new standard for quantification of the hyperpolarization in EPR experiments, and demonstrate a significant increase in the optically generated 1H NMR signal enhancement upon addition of glycerol to aqueous solutions.

AB - Spin hyperpolarization can dramatically increase signal intensities in magnetic resonance experiments, providing either improved bulk sensitivity or additional spectroscopic detail through selective enhancements. While typical hyperpolarization approaches have utilized microwave irradiation, one emerging route is the use of optically generated triplet states. We report an investigation into the effects of solution viscosity on radical–triplet pair interactions, propose a new standard for quantification of the hyperpolarization in EPR experiments, and demonstrate a significant increase in the optically generated 1H NMR signal enhancement upon addition of glycerol to aqueous solutions.

KW - Nuclear magnetic resonance (NMR)

KW - electron paramagnetic resonance (EPR)

U2 - 10.1039/D0CP04012F

DO - 10.1039/D0CP04012F

M3 - Article

JO - Physical Chemistry Chemical Physics

JF - Physical Chemistry Chemical Physics

SN - 1463-9076

ER -

Viscosity effects on optically generated electron and nuclear spin hyperpolarization

Abstract

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Exploiting Radical Triplet Pair Hyperpolarization for Sensitivity Enhancement in Solution-State NMR

Cite this